Method for synthesis of substituted 2-alkylthio-7-amino-6-cyano(ethoxycarbonyl)-5H-pyrano[2,3-d] pyrimidine-4(3H)-ones

被引：0
|
作者：
机构：
[1] Dyachenko, V.D.
[2] Posternak, A.G.
来源：
Dyachenko, V.D. | 2005年 / Naukova Dumka卷 / 71期
关键词：
Aldehydes - Chemical analysis - Esters - Infrared spectroscopy - Nitrogen compounds - Nuclear magnetic resonance spectroscopy - Sulfur compounds;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The multicomponent condensation of 2-thiobarbituric acid, aldehydes, malononitrile or ethyl cyanoacetate, alkyl halides and morpholine was studied. It is shown that the condensation products are substituted 2-alkylthio-7-amino-6-cyano(ethoxycarbonyl)-5H-pyrano- [2,3-d]pyrimidines. The products were characterized by IR and NMR spectroscopy and elemental analysis.
引用
收藏
页码：7 / 8
相关论文
共 50 条
  • [21] General method for the preparation of substituted 2-amino-4H,5H-pyrano[4,3-b]pyran-5-ones and 2-amino-4H-pyrano[3,2-c]pyridine-5-ones
    Stoyanov, EV
    Ivanov, IC
    Heber, D
    MOLECULES, 2000, 5 (01) : 19 - 32
  • [22] New efficient synthesis of 2-substituted 5,6,7,8-tetrahydro-benzothieno[2,3-d]pyrimidin-4(3H)-ones
    Ding, MW
    Yang, SJ
    Zhu, J
    SYNTHESIS-STUTTGART, 2004, (01): : 75 - 79
  • [23] Design, Synthesis, and Evaluation of the Antitubercular Activity of 5-Phenyl Substituted-5, 6-dihydropyrido[2, 3-d]pyrimidine-4, 7(3H, 8H)-dione Compounds
    Sun, Lianqi
    Kou, Shibo
    Wang, Bin
    Wang, Yongjian
    Meng, Jianzhou
    Liu, Tianfu
    Ma, Yuanyuan
    Zhao, Jianyuan
    Yi, Hong
    Cen, Shan
    Lu, Yu
    Li, Zhuorong
    JOURNAL OF MEDICINAL CHEMISTRY, 2024, 67 (17) : 14927 - 14945
  • [24] SYNTHESIS AND SPECTRAL PROPERTIES OF PYRROLO[3',4'-5,6]-4H-PYRANO[2,3-D]PYRIMIDINE DERIVATIVES
    MARCHALIN, S
    PAVLIKOVA, F
    ILAVSKY, D
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1989, 54 (05) : 1336 - 1345
  • [25] Synthesis of substituted 6-amino-4-aryl-5-cyano-2h,4h-pyrano[2,3-c]pyrazoles. Crystal and molecular structure of 6-amino-5-cyano-3-methyl-4-(2′,4′,6′-triethylphenyl)-2h,4h -pyrano[2,3-c]pyrazole
    Shestopalov A.M.
    Yakubov A.P.
    Tsyganov D.V.
    Emel'yanova Yu.M.
    Nesterov V.N.
    Chemistry of Heterocyclic Compounds, 2002, 38 (10) : 1180 - 1189
  • [26] Carboxylic acid anhydrides in the synthesis of 5H-pyrano[2,3-d : 6,5-d′]dipyrimidine derivatives
    Moskvin, AV
    Meshcheryakov, MP
    Reznikova, NR
    Koz'mina, AG
    Ivin, BA
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2000, 70 (05) : 821 - 822
  • [27] Substituted 6-amino-4-aryl-5-cyano-2H,4H-pyrano[2,3-c]pyrazoles.: Crystal and molecular structure of 6-amino-5-cyano-3-methyl-4-(2′,4′,6′-triethylphenyl)-2H,4H-pyrano[2,3-c]pyrazole
    Shestopalov, AM
    Yakubov, AP
    Tsyganov, DV
    Emelianova, YM
    Nesterov, VN
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2002, (10): : 1345 - 1354
  • [28] A Catalyst-Free Aqueous Synthesis of 2-Amino-7,9-dihydrothieno[3,2:5,6]pyrido[2,3-d]pyrimidine-4,6(3H,5H)-dione Derivatives
    Yao, Changsheng
    Lu, Ting
    Yu, Chenxia
    Wang, Xiangshan
    Li, Tuanjie
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 : E163 - E166
  • [29] Synthesis of 2-substituted pyrano[2,3-d]pyrimidin-4(3H)-one derivatives using iminophosphorane
    Re, Qing-Yun
    He, Hong-Wu
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2008, 183 (2-3) : 629 - 630
  • [30] SYNTHESIS OF 2-MERCAPTOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONES
    DEVANI, MB
    SHISHOO, CJ
    PATHAK, US
    SHARMA, BG
    GOKHALE, SV
    PADHYA, AC
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1977, 15 (06): : 575 - 577
12345