Progress in the Research of Synthetic Biology in Construction of Engineered Microorganisms

被引：1

作者：

Gao X. ^{[1
]}

Liu Y. ^{[1
]}

Jiang Z. ^{[1
]}

Zeng Q. ^{[1
]}

Liu S. ^{[1
]}

Liu X. ^{[1
]}

Min W. ^{[1
]}

机构：

[1] National Engineering Laboratory on Wheat and Corn Further Processing, College of Food Science and Engineering, Jilin Agricultural University, Changchun

来源：

Shipin Kexue/Food Science | 2022年 / 43卷 / 15期

关键词：

Construction of engineered microorganisms; Genome editing; Metabolic regulation; Synthetic biology;

D O I：

10.7506/spkx1002-6630-20210831-414

中图分类号：

学科分类号：

摘要：

As a new interdisciplinary subject that covers many fields in the 21st century, synthetic biology is of great help in exploring the basic laws of life activities and biotechnological innovations and breakthroughs. Synthetic biotechnology is a new approach to construct engineered microorganisms. It has been widely used to produce amino acids, organic acids, aromatic compounds, sugars, and so on. The yield of target products produced by recombinant engineered microorganisms can be efficiently increased by using advanced modules, systematic design and new genome editing methods to engineer the complex metabolic pathways in type strains, promoting the rapid development of social productivity. In this paper, the latest advances in the application of synthetic biology for the construction of engineered microorganism are reviewed, the developmental course of synthetic biotechnology is elaborated, and its application for the construction of engineered microorganism is exemplified. With the deepening of research on engineered microorganisms, synthetic biotechnology will bring new breakthroughs and opportunities for the fermentation industry. © 2022, China Food Publishing Company. All right reserved.

引用

页码：256 / 264

页数：8

共 54 条

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