Biomimetic selenium nanosystems for infectious wound healing

被引:0
|
作者
Fang M. [1 ]
Zhang H. [2 ]
Wang Y. [1 ]
Zhang H. [2 ]
Zhang D. [1 ]
Xu P. [1 ]
机构
[1] Department of Hematology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing
[2] State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing
来源
Engineered Regeneration | 2023年 / 4卷 / 02期
基金
中国国家自然科学基金;
关键词
Biomimetic; Red blood cell membrane; Selenium nanoparticle; Wound healing;
D O I
10.1016/j.engreg.2023.01.004
中图分类号
学科分类号
摘要
Bacteria-related wound infection and healing have been a major issue for patients and health-care systems for decades. The rise and evolution of effective treatment will result in significant benefits to human beings. In addition to standard antibacterial drugs, a combination of nanoparticles (NPs) and biological membranes is widely applied as a novel antibacterial agent against infectious pathogens. In this paper, the red blood cell membrane-encapsulated selenium nanoparticles (R-SeNPs) were fabricated for infectious wound healing. The stability, the immune evading capability, and the internal circulation time of the R-SeNPs were notably enhanced compared with those of bare selenium nanoparticles (SeNPs). Moreover, in vivo studies demonstrated the outstanding performance of the R-SeNPs in infectious wound healing. The biomimetic selenium nanosystem demonstrated the benefits of the combination of nanotechnology and bionics design and will contribute to wound healing in the future. © 2023
引用
收藏
页码:152 / 160
页数:8
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