Based on the practice of translation teaching in private colleges and universities, this research summarizes the research on corpus translation and translation research conducted by domestic and foreign scholars, and combines the application-oriented translation of private colleges and universities with the orientation of training goals, curriculum group design, teaching content selection, and implementation path planning so as to propose a new corpus-based micro-course teaching model. The results of teaching practice show that the new teaching mode is helpful to optimize the professional development teaching ecological environment of student translators, improve their English-Chinese bilingual expression level, diversify their learning methods, and significantly improve their sustainable and autonomous learning ability. In view of this, translation teaching in the construction of micro-translation major should further enrich corpus teaching resources and dynamically track students' use of corpus; translation teachers need to continuously improve corpus use technology, improve interdisciplinary ability, and adapt to the teaching reform of micro-translation major under the new situation needs.