New Antibacterial 1,3,4-Thiadiazole Derivatives With Pyridine Moiety

被引：3
|
作者：
Sener, Nesrin [1 ]
Aldwib, Aiman Emhemad Omeran [2 ]
机构：
[1] Kastamonu Univ, Fac Sci, Dept Chem, TR-37200 Kastamonu, Turkiye
[2] Kastamonu Univ, Inst Sci, TR-37200 Kastamonu, Turkiye
来源：
CHEMISTRY & BIODIVERSITY | 2024年 / 21卷 / 06期
关键词：
Pyridine; 1,3,4-thiadiazole; antibacterial; CYTOTOXICITY EVALUATION; EFFICIENT SYNTHESIS; MOLECULAR DOCKING; THIAZOLES; 2-AMINO-1,3,4-THIADIAZOLE; THIADIAZOLES; PERSPECTIVE; ANTICANCER; CHEMISTRY; POTENT;
D O I：
10.1002/cbdv.202400522
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1,3,4-Thiadiazole compounds were synthesized using pyridine carboxylic acid derivatives and thiosemicarbazide derivatives. The molecular structures of the resulting compounds were characterized by spectroscopic methods such as ATR-FTIR, 1H-NMR, and elemental analysis. Its compounds were also examined for their antibacterial properties against some strains of bacteria. Five synthesized compounds showed varying antibacterial effects on Escherichia coli, Salmonella kentucky, Bacillus substilis and Klebsiella pneumoniae. This result revealed that some of the resulting compounds could be antibacterial agents. image
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页数：10
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