New Antibacterial 1,3,4-Thiadiazole Derivatives With Pyridine Moiety

被引：3
|
作者：
Sener, Nesrin [1 ]
Aldwib, Aiman Emhemad Omeran [2 ]
机构：
[1] Kastamonu Univ, Fac Sci, Dept Chem, TR-37200 Kastamonu, Turkiye
[2] Kastamonu Univ, Inst Sci, TR-37200 Kastamonu, Turkiye
来源：
CHEMISTRY & BIODIVERSITY | 2024年 / 21卷 / 06期
关键词：
Pyridine; 1,3,4-thiadiazole; antibacterial; CYTOTOXICITY EVALUATION; EFFICIENT SYNTHESIS; MOLECULAR DOCKING; THIAZOLES; 2-AMINO-1,3,4-THIADIAZOLE; THIADIAZOLES; PERSPECTIVE; ANTICANCER; CHEMISTRY; POTENT;
D O I：
10.1002/cbdv.202400522
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1,3,4-Thiadiazole compounds were synthesized using pyridine carboxylic acid derivatives and thiosemicarbazide derivatives. The molecular structures of the resulting compounds were characterized by spectroscopic methods such as ATR-FTIR, 1H-NMR, and elemental analysis. Its compounds were also examined for their antibacterial properties against some strains of bacteria. Five synthesized compounds showed varying antibacterial effects on Escherichia coli, Salmonella kentucky, Bacillus substilis and Klebsiella pneumoniae. This result revealed that some of the resulting compounds could be antibacterial agents. image
引用
收藏
页数：10
相关论文
共 50 条
  • [31] Derivatives Bearing 1, 3, 4-Thiadiazole Moiety
    Wan J.
    Wu S.
    Gan Y.
    Meng J.
    Wang Z.
    Ouyang G.
    Wang, Zhenchao (wzc.4884@163.com), 1683, Higher Education Press Limited Company (39): : 1683 - 1690
  • [32] Discovery of novel carbazole derivatives containing a 1,3,4-thiadiazole moiety as antifungal candidates
    Tang, Chenghao
    Chen, Xingju
    Yang, Shengzhou
    Guo, Wenbo
    Yang, Xiumei
    Li, Pei
    Wang, Xiang
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2023, 198 (08) : 627 - 631
  • [33] Synthesis and antitumor activity of novel pyridazinone derivatives containing 1,3,4-thiadiazole moiety
    Qin, Junhu
    Zhu, Mei
    Zhu, Hongmei
    Zhang, Liqiong
    Fu, Yihong
    Liu, Jiamin
    Wang, Zhenchao
    OuYang, Guiping
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2020, 195 (07) : 592 - 599
  • [34] MICROWAVE SPECTRA OF 1,3,4-THIADIAZOLE AND [34S]1,3,4-THIADIAZOLE - DIPOLE MOMENT OF 1,3,4-THIADIAZOLE
    BAK, B
    LIPSCHITZ, L
    RASTRUPANDERSEN, J
    CHRISTENSEN, D
    HANSENNYGAARD, L
    JOURNAL OF MOLECULAR SPECTROSCOPY, 1962, 9 (03) : 225 - &
  • [35] Thiobenzohydrazides and Dithiocarbazates in the Synthesis of New 1,3,4-Thiadiazine and 1,3,4-Thiadiazole Derivatives
    Kuz'mich, N. N.
    Lalaev, B. Yu.
    Yakovlev, I. P.
    Semakova, T. L.
    Zakhs, V. E.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2009, 79 (07) : 1583 - 1584
  • [36] New 1,3,4-Thiadiazole Derivatives: Synthesis, Characterization, and Antimicrobial Activity
    Abo-Bakr, Ahmed M.
    Hashem, Heba E.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (03) : 1038 - 1047
  • [37] Synthesis of Some New 1,3,4-Thiadiazole Derivatives and Antifungal Studies
    Kumar, Vikas
    Singh, Pratibha
    ASIAN JOURNAL OF CHEMISTRY, 2010, 22 (09) : 6829 - 6839
  • [38] Synthesis of New 1,3,4-Thiadiazole Derivatives Containing of Morpholine Ring
    Hamidian, H.
    Afrooz, M.
    Fozooni, S.
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (01) : 487 - 489
  • [39] Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
    Altintop, Mehlika Dilek
    Can, Ozgur Devrim
    Ozkay, Umide Demir
    Kaplancikli, Zafer Asim
    MOLECULES, 2016, 21 (08)
  • [40] Thiobenzohydrazides and dithiocarbazates in the synthesis of new 1,3,4-thiadiazine and 1,3,4-thiadiazole derivatives
    N. N. Kuz’mich
    B. Yu. Lalaev
    I. P. Yakovlev
    T. L. Semakova
    V. E. Zakhs
    Russian Journal of General Chemistry, 2009, 79 : 1583 - 1584
12345