A high-speed near-infrared optical coherence tomography angiography system for mouse retina

被引:2
|
作者
Yi, Wei [1 ,2 ]
Hu, Kaixuan [1 ,2 ]
Wan, Yi [1 ,2 ]
Wu, Fuwang [1 ,2 ]
Song, Weiye [1 ,2 ]
机构
[1] Shandong Univ, Sch Mech Engn, Jinan 250061, Shandong, Peoples R China
[2] Shandong Univ, Key Lab High Efficiency & Clean Mech Manufacture, Minist Educ, Jinan 250061, Shandong, Peoples R China
基金
中国国家自然科学基金;
关键词
Optical coherence tomography angiography; High speed; Retinal imaging; Near-infrared; RESOLUTION; OCT;
D O I
10.1016/j.jlumin.2024.120550
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Optical coherence tomography angiography (OCTA) is a non-contact, high-resolution biomedical imaging technology widely used in eye disease diagnosis. This paper introduces a novel mouse retinal near-infrared imaging system with a spectral domain OCTA operating at a 250 kHz A-scan rate. The system achieves a 2.3 mu m axial resolution and a 1.2 mm, 5.7 dB imaging range. With a robust signal-to-noise ratio of 99.95 dB at 250 kHz A-scan, after optimizing the scanning parameters, the system captured clear retinal cross-sections, optical coherence tomography (OCT) scans, and OCTA images during the imaging process of the mouse retina.
引用
收藏
页数:6
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