Rare-variant association study

被引：0

作者：

Wang, Yin ^{[1
]}

Chan, Ying Wai ^{[1
]}

机构：

[1] Univ Hong Kong, Sch Biol Sci, Pokfulam, Hong Kong, Peoples R China

来源：

CELL GENOMICS | 2024年 / 4卷 / 05期

关键词：

MISSING HERITABILITY;

D O I：

10.1016/j.xgen.2024.100558

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this issue of Cell Genomics , Wang, Liu, Zuo, Wang, et al. 1 investigate rare variants in hepatocellular carcinoma (HCC) by performing the first rare -variant association study (RVAS) in a Chinese population cohort. It uncovers BRCAness phenotypes associated with the NRDE2-p.N377I variant, suggesting PARP inhibitors as a promising therapeutic approach for certain HCC patients.

引用

页数：2

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