As the threat of natural disasters such as droughts, floods, forest fires, and landslides increases due to climate change, social demand for high-resolution soil moisture retrieval, such as Synthetic Aperture Radar (SAR), is also increasing. However, the domestic environment has a high proportion of mountainous topography, making it challenging to retrieve soil moisture from SAR data. This study evaluated the usability of Sentinel-1 SAR, which is applied with the Artificial Neural Network (ANN) technique, to retrieve soil moisture. It was confirmed that the backscattering coefficient obtained from Sentinel-1 significantly correlated with soil moisture behavior, and the possibility of stand-alone use to correct vegetation effects without using auxiliary data observed from other satellites or observatories. However, there was a large difference in the characteristics of each site and topographic group. In particular, when the model learned on the mountain and at flat land cross-applied, the soil moisture could not be properly simulated. In addition, when the number of learning points was increased to solve this problem, the soil moisture retrieval model was smoothed. As a result, the overall correlation coefficient of all sites improved, but errors at individual sites gradually increased. Therefore, systematic research must be conducted in order to widely apply high-resolution SAR soil moisture data. It is expected that it can be effectively used in various fields if the scope of learning sites and application targets are specifically limited.