Digital light processing (DLP) 3D printing of polymer networks comprising virus-like particles

被引：1

作者：

Sadaba, Naroa ^{[1
]}

Bayon, Jorge Leganes ^{[2
,3
,4
]}

Nelson, Alshakim ^{[1
]}

Steinmetz, Nicole F. ^{[2
,3
,4
,5
,6
,7
,8
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

[2] Univ Calif San Diego, Aiiso Yufeng Li Family Dept Chem & Nano Engn, 9500 Gilman Dr, La Jolla, CA 92093 USA

[3] Univ Calif San Diego, Dept Bioengn, 9500 Gilman Dr, La Jolla, CA 92093 USA

[4] Univ Calif San Diego, Dept Radiol, 9500 Gilman Dr, La Jolla, CA 92093 USA

[5] Univ Calif San Diego, Ctr Nanoimmunoengn, 9500 Gilman Dr, La Jolla, CA 92093 USA

[6] Univ Calif San Diego, Shu & K C Chien & Peter Farrell Collaboratory, 9500 Gilman Dr, San Diego, CA 92093 USA

[7] Univ Calif San Diego, Inst Engn Med, Ctr Engn Canc, 9500 Gilman Dr, La Jolla, CA 92093 USA

[8] Univ Calif San Diego, Moores Canc Ctr, 9500 Gilman Dr, La Jolla, CA 92093 USA

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 72期

关键词：

3D printing - Addition reactions - Biopolymers - Polyethylene glycols - Viruses;

D O I：

10.1039/d4cc02411g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this work, we introduce a 3D-printable virus-like particle (VLP)-enhanced cross-linked biopolymer system. VLPs displaying surface-available acrylate groups were prepared through aza-Michael addition to serve as resins. The VLP resins were then photopolymerized into a poly(ethylene glycol) diacrylate (PEGDA) network following DLP 3D printing. This approach represents a convergence of disciplines, where the synergistic interaction between virology and additive manufacturing unlocks new frontiers in biotechnology. In this work, we introduce a 3D-printable virus-like particle (VLP)-enhanced cross-linked biopolymer system.

引用

页码：9733 / 9736

页数：5

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