Neuroprotective effect of sea urchins (Diadema savignyi) extract in an animal model of aluminum neurotoxicity

被引：0
|
作者：
Rofida Zagloul [1 ]
Eman A. Khalil [1 ]
Nada M. Ezzelarab [1 ]
Ahmed Abdellatif [1 ]
机构：
[1] The American University in Cairo,Department of Biology, School of Sciences and Engineering
来源：
Blue Biotechnology | / 1卷 / 1期
关键词：
Neurotoxicity; Neuroprotection; Sea urchin; Heavy metal toxicity; Aluminum toxicity; Oxidative stress; GFAP; Caspase 3;
D O I：
10.1186/s44315-024-00001-x
中图分类号：
学科分类号：
摘要：
Human exposure to heavy metals causes major health consequences. Aluminum (Al) toxicity primarily affects the brain and has been implicated in neurodegenerative disorders. Natural products offer a cheap and safe source of protective agents against heavy metal toxicity. This study investigates the neuroprotective role of the shell extract (SH) from the Sea urchin (Diadema savignyi) collected from the Red Sea in an Aluminum-induced neurotoxicity model.
引用
收藏
相关论文
共 50 条
  • [41] Evaluation of possible neuroprotective effects of virgin coconut oil on aluminum-induced neurotoxicity in an in vitro Alzheimer's disease model
    Demirel, Goksun
    Sanajou, Sonia
    Yirun, Anil
    Cakir, Deniz Arca
    Berkkan, Aysel
    Baydar, Terken
    Erkekoglu, Pinar
    JOURNAL OF APPLIED TOXICOLOGY, 2024, 44 (04) : 609 - 622
  • [42] Neuroprotective Effect of Green Tea Polyphenol, EGCG in Animal Model of Parkinson's Disease
    Reddy, Manju B.
    Xu, Qi
    Zhou, Ying
    Kanthasamy, Anumantha G.
    FASEB JOURNAL, 2008, 22
  • [43] Potential neuroprotective effect of Anakinra in spinal cord injury in an in vivo experimental animal model
    Hasturk, Askin E.
    Yilmaz, Erdal R.
    Turkoglu, Erhan
    Arikan, Murat
    Togral, Guray
    Hayirli, Nazli
    Erguder, Berrin I.
    Evirgen, Oya
    NEUROSCIENCES, 2015, 20 (02) : 124 - 130
  • [44] DENTAL PULP STROMAL CELLS: NEUROPROTECTIVE EFFECT IN AN ANIMAL MODEL OF PARKINSON'S DISEASE
    Fracaro, L.
    Azevedo, E.
    Hochuli, A. H. D.
    Ilkiw, J. L.
    Bail, E. L.
    Capriglione, L. G. A.
    Lima, M. M. S.
    Brofman, P. R. S.
    Senegaglia, A. C.
    CYTOTHERAPY, 2022, 24 (10) : S27 - S27
  • [45] THE NEUROPROTECTIVE EFFECT OF ELECTRO-ACUPUNCTURE AGAINST ISCHEMIC STROKE IN ANIMAL MODEL: A REVIEW
    Feng, Rui
    Zhang, Feng
    AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 2014, 11 (03) : 25 - 29
  • [46] Neuroprotective effect of cerebrolysin and erythropoietin versus haloperidol in an Alzheimer's disease - animal model
    Mogoanta, L.
    Marinescu, D.
    Udristoiu, T.
    Udristoiu, I.
    Pirici, D.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2010, 20 : S565 - S566
  • [47] Neuroprotective Effect of Aqueous Extract of Selaginella delicatula as Evidenced by Abrogation of Rotenone-Induced Motor Deficits, Oxidative Dysfunctions, and Neurotoxicity in Mice
    Girish Chandran
    Cellular and Molecular Neurobiology, 2013, 33 : 929 - 942
  • [48] Neuroprotective Effect of Aqueous Extract of Selaginella delicatula as Evidenced by Abrogation of Rotenone-Induced Motor Deficits, Oxidative Dysfunctions, and Neurotoxicity in Mice
    Chandran, Girish
    Muralidhara
    CELLULAR AND MOLECULAR NEUROBIOLOGY, 2013, 33 (07) : 929 - 942
  • [49] Apocynin exerts neuroprotective effects in fumonisin b1-induced neurotoxicity via attenuation of oxidative stress and apoptosis in an animal model
    Krishnaswamy, Krupashree
    Manasa, Vallamkondu
    Khan, Mohammed Touseef
    Peddha, Muthukumar Serva
    JOURNAL OF FOOD SCIENCE, 2024, 89 (02) : 1280 - 1293
  • [50] Neuroprotective and Cognitive-Enhancing Effects of Microencapsulation of Mulberry Fruit Extract in Animal Model of Menopausal Women with Metabolic Syndrome
    Kawvised, Supannika
    Wattanathorn, Jintanaporn
    Thukham-mee, Wipawee
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017, 2017
12345