Neuroprotective effect of sea urchins (Diadema savignyi) extract in an animal model of aluminum neurotoxicity

被引:0
|
作者
Rofida Zagloul [1 ]
Eman A. Khalil [1 ]
Nada M. Ezzelarab [1 ]
Ahmed Abdellatif [1 ]
机构
[1] The American University in Cairo,Department of Biology, School of Sciences and Engineering
来源
Blue Biotechnology | / 1卷 / 1期
关键词
Neurotoxicity; Neuroprotection; Sea urchin; Heavy metal toxicity; Aluminum toxicity; Oxidative stress; GFAP; Caspase 3;
D O I
10.1186/s44315-024-00001-x
中图分类号
学科分类号
摘要
Human exposure to heavy metals causes major health consequences. Aluminum (Al) toxicity primarily affects the brain and has been implicated in neurodegenerative disorders. Natural products offer a cheap and safe source of protective agents against heavy metal toxicity. This study investigates the neuroprotective role of the shell extract (SH) from the Sea urchin (Diadema savignyi) collected from the Red Sea in an Aluminum-induced neurotoxicity model.
引用
收藏
相关论文
共 50 条
  • [31] Cognitive enhancing effect and neuroprotective effect of rice berry in animal model of Alzheimer's disease
    Tiamkao, S.
    Wattanathorn, J.
    Pannangrong, W.
    Muchimapura, S.
    Tong-un, T.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 285 : S274 - S274
  • [32] Sea Anemone Kunitz-Type Peptides Demonstrate Neuroprotective Activity in the 6-Hydroxydopamine Induced Neurotoxicity Model
    Sintsova, Oksana
    Gladkikh, Irina
    Monastyrnaya, Margarita
    Tabakmakher, Valentin
    Yurchenko, Ekaterina
    Menchinskaya, Ekaterina
    Pislyagin, Evgeny
    Andreev, Yaroslav
    Kozlov, Sergey
    Peigneur, Steve
    Tytgat, Jan
    Aminin, Dmitry
    Kozlovskaya, Emma
    Leychenko, Elena
    BIOMEDICINES, 2021, 9 (03)
  • [33] Neuroprotective role of Diosgenin, a NGF stimulator, against Aβ (1-42) induced neurotoxicity in animal model of Alzheimer's disease
    Som, Swati
    Antony, Justin
    Dhanabal, SPalanisamy
    Ponnusankar, Sivasankaran
    METABOLIC BRAIN DISEASE, 2022, 37 (02) : 359 - 372
  • [34] Possible neuroprotective mechanism of resveratrol on 3-nitroproplonic acid-induced neurotoxicity, an animal model of Huntington's disease
    Kumar, A.
    Kumar, P.
    Padi, S. S., V
    Naidu, P. S.
    JOURNAL OF NEUROCHEMISTRY, 2006, 98 : 98 - 98
  • [35] Neuroprotective effect of Reseda luteola L. extract in a mouse neuronal cell model
    Seong Soon Kim
    Ji Yeon Seo
    Soon Sung Lim
    Hwa Jin Suh
    Lione Kim
    Jong-Sang Kim
    Food Science and Biotechnology, 2015, 24 : 333 - 339
  • [36] Investigation of Neuroprotective Effect of Shilajit Extract in Experimental Head Trauma Model Created in Rats
    Karaoglu, Adil Can
    Atci, Ibrahim Burak
    Demirel, Nail
    Turk, Okan
    Hurdag, Canan
    Baran, Ozgur
    Ozdemir, Nuriye Guzin
    Kocak, Ayhan
    Karakurt, Muhammet Teoman
    TURKISH NEUROSURGERY, 2023, 33 (06) : 976 - 981
  • [37] Neuroprotective Effect of Ashwagandha Extract against the Neurochemical Changes Induced in Rat Model of Hypothyroidism
    Hosny, Eman N.
    El-Gizawy, Mayada M.
    Sawie, Hussein G.
    Abdel-Wahhab, Khaled G.
    Khadrawy, Yasser A.
    JOURNAL OF DIETARY SUPPLEMENTS, 2021, 18 (01) : 72 - 91
  • [38] The neuroprotective effect of Ginkgo biloba extract on retinal ganglion cells in a rat glaucoma model
    Lee, VW
    Lai, C
    Yip, HK
    Wu, W
    So, KF
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 : U25 - U25
  • [39] Neuroprotective effect of Reseda luteola L. extract in a mouse neuronal cell model
    Kim, Seong Soon
    Seo, Ji Yeon
    Lim, Soon Sung
    Suh, Hwa Jin
    Kim, Lione
    Kim, Jong-Sang
    FOOD SCIENCE AND BIOTECHNOLOGY, 2015, 24 (01) : 333 - 339
  • [40] NEUROPROTECTIVE EFFECT OF EXTRACT OF ANACARDIUM OCCIDENTALE LINN ON A ROTENONE MODEL OF PARKINSON'S DISEASE
    Barreto Linard-Medeiros, Cybelle Facanha
    Wanderley Sales, Victor de Albuquerque
    Ramos, Adriano Costa
    Sereniki, Adriana
    Salles Trevisan, Maria Teresa
    Wanderley, Almir Goncalves
    Lopes Lafayette, Simone Sette
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2015, 6 (01): : 123 - 129