Photoredox-Enabled Synthesis of α-Alkylated Alkenylammonium Salts

被引：0

作者：

Tonedachi, Rina ^{[1
]}

Yoshita, Aoi ^{[1
]}

Sakakibara, Yota ^{[1
]}

Murakami, Kei ^{[1
,2
]}

机构：

[1] Kwansei Gakuin Univ, Sch Sci & Technol, Dept Chem, Gakuen Uegahara 1, Sanda, Hyogo 6691330, Japan

[2] JST PRESTO, 7 Gobancho,Chiyoda, Tokyo 1020076, Japan

来源：

SYNTHESIS-STUTTGART | 2024年 / 56卷 / 21期

基金：

日本科学技术振兴机构;

关键词：

alkenylammonium salts; photoredox catalyst; alkylation; halogen-atom transfer; quaternary ammonium salts; ATOM TRANSFER; RADICALS; GENERATION;

D O I：

10.1055/a-2302-5887

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The development of novel synthetic methods for quaternary ammonium salts is highly demanded since the current synthesis heavily relies on the conventional Menshutkin reaction. Herein, we report photoredox-catalyzed alkylation of alpha-brominated alkenylammonium salts. Mechanistically, the generation of a highly reactive alpha-ammoniovinyl radical is the key to our method. This reaction enables thesynthesis of various unprecedented alpha-alkylated alkenylammonium salts.

引用

页码：3341 / 3347

页数：7

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