REPEAT SEQUENCES IN THE GENE ENCODING THE HUMAN D4 DOPAMINE RECEPTOR

被引:6
|
作者
ODOWD, BF [1 ]
机构
[1] ADDICT RES FDN,TORONTO M5S 1A8,ONTARIO,CANADA
关键词
G-PROTEIN-COUPLED RECEPTORS; 3RD CYTOPLASMIC LOOP; PARALOG; INTRON EXON;
D O I
10.1016/0378-1119(92)90207-6
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The gene encoding the human D4 dopamine receptor has evolved by gaining at least five internal repeats which are located within exons 3 and 4, and in the intervening intron 3 sequence. The amino acid sequence in the cytoplasmic loop of the receptor, involved in G protein coupling, has been altered by these gene changes.
引用
收藏
页码:301 / 302
页数:2
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