MOLECULAR RECOGNITION - MODELS FOR DRUG DESIGN

被引：7

作者：

BRECKENRIDGE, RJ

机构：

[1] Drug Design Group, Sandoz Pharma Ltd., Basel

来源：

EXPERIENTIA | 1991年 / 47卷 / 11-12期

关键词：

MOLECULAR RECOGNITION; MODELING; NMR; STRUCTURE; X-RAY;

D O I：

10.1007/BF01918379

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The review takes examples, mostly from the recent literature, to illustrate how an understanding of physico-chemical properties and an appreciation of the molecular shape and electronic properties can lead to a better insight into molecular recognition processes. The techniques used to generate 3-dimensional structures of molecules and the influence this information has had on the drug design cycle, are briefly discussed.

引用

页码：1148 / 1161

页数：14

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