MOLECULAR RECOGNITION - MODELS FOR DRUG DESIGN

被引：7
|
作者：
BRECKENRIDGE, RJ
机构：
[1] Drug Design Group, Sandoz Pharma Ltd., Basel
来源：
EXPERIENTIA | 1991年 / 47卷 / 11-12期
关键词：
MOLECULAR RECOGNITION; MODELING; NMR; STRUCTURE; X-RAY;
D O I：
10.1007/BF01918379
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The review takes examples, mostly from the recent literature, to illustrate how an understanding of physico-chemical properties and an appreciation of the molecular shape and electronic properties can lead to a better insight into molecular recognition processes. The techniques used to generate 3-dimensional structures of molecules and the influence this information has had on the drug design cycle, are briefly discussed.
引用
收藏
页码：1148 / 1161
页数：14
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