EXPERIMENTS DIRECTED TOWARDS THE SYNTHESIS OF ANTHRACYCLINONES .14. AN INTERMEDIATE FOR THE SYNTHESIS OF VINEOMYCINS

被引：15
|
作者：
CAMBIE, RC [1 ]
HOWE, TA [1 ]
PAUSLER, MG [1 ]
RUTLEDGE, PS [1 ]
WOODGATE, PD [1 ]
机构：
[1] UNIV AUCKLAND, DEPT CHEM, AUCKLAND, NEW ZEALAND
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 1987年 / 40卷 / 06期
关键词：
D O I：
10.1071/CH9871063
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Anthrarufin (4) has been converted by a high-yielding route involving sequential reductive Claisen rearrangements into 1-acetoxy-5-methoxy-9,10-dioxo-6-(2''-oxopropyl)-9,10-dihydroanthracene-2-carbaldehyde (3), an intermediate which is suitable for the synthesis of vineomycins. The thermal Claisen rearrangements of some allyl ethers of 1,5-dihydroxyanthraquinone have been examined.
引用
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页码：1063 / 1072
页数：10
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