COMPLEMENTARY-DNA CLONING AND NUCLEOTIDE-SEQUENCE OF RABBIT SERUM AMYLOID A PROTEIN

被引：15
|
作者：
RAY, BK [1 ]
RAY, A [1 ]
机构：
[1] UNIV MISSOURI,COLL VET MED,DEPT VET PATHOL,COLUMBIA,MO 65211
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 178卷 / 01期
关键词：
D O I：
10.1016/0006-291X(91)91780-G
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A complementary DNA clone encoding serum amyloid A protein has been isolated from an acute rabbit liver cDNA library. Complete nucleotide sequence analysis reveals that the cloned gene contains a 24 bases 5′ untranslated region, 369 bases coding region and a 106 bases 3′ untraslated region. Primer extension analysis indicates that the full-length 5′ untranslated region contains 80 nucleotides. Northern blot analysis of mRNA from normal and acute rabbit livers demonstrates that this gene is expressed constitutively at a low level and undergoes induction of transcription in response to acute inflammation by the administration of turpentine. © 1991.
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页码：68 / 72
页数：5
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