EFFECTS OF ALPRAZOLAM ON T-CELL IMMUNOSUPPRESSIVE RESPONSE TO SURGICAL STRESS IN MICE

被引：23
|
作者：
FREIREGARABAL, M [1 ]
BELMONTE, A [1 ]
ORALLO, F [1 ]
COUCEIRO, J [1 ]
NUNEZ, MJ [1 ]
机构：
[1] UNIV SANTIAGO DE COMPOSTELA, FAC MED, DEPT PHARMACOL, E-15705 SANTIAGO, SPAIN
来源：
CANCER LETTERS | 1991年 / 58卷 / 03期
关键词：
STRESS; IMMUNITY; LYMPHOCYTES-T; BLASTIC RESPONSE; ALPRAZOLAM; ANXIOLYTICS; ADRENOCORTICOTROPIC HORMONE;
D O I：
10.1016/0304-3835(91)90098-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Mice submitted to surgical stress induced by laparotomy and treated with chronic alprazolam (1 mg/kg) showed a reduction in stress-induced suppression of thymus and spleen cellularity, as well as in peripheral T lymphocyte population. The blastic response of spleen lymphoid cells was also assessed and found to partially supress the inhibitory effect of surgery.
引用
收藏
页码：183 / 187
页数：5
相关论文
共 50 条
  • [21] T-CELL RESPONSE IN MICE AGAINST BORELLIA-BURGDORFERI
    SCHAIBLE, UE
    KRAMER, MD
    JUSTUS, K
    MUSETEANU, C
    SIMON, M
    IMMUNOBIOLOGY, 1988, 178 (1-2) : 67 - 68
  • [22] Influence of maternal immunity on antibody and T-cell response in mice
    Blomqvist, GAM
    Lövgren-Bengtsson, K
    Morein, B
    VACCINE, 2003, 21 (17-18) : 2022 - 2031
  • [23] ANALYSIS OF THE SPONTANEOUS T-CELL RESPONSE TO INSULIN IN NOD MICE
    WEGMANN, DR
    GILL, RG
    NORBURYGLASER, M
    SCHLOOT, N
    DANIEL, D
    JOURNAL OF AUTOIMMUNITY, 1994, 7 (06) : 833 - 843
  • [24] T-cell response
    Blacklaws, B
    TRENDS IN MICROBIOLOGY, 1998, 6 (08) : 305 - 305
  • [25] The Effects of Oxidative Stress on Dendritic Cell Migration and T-Cell Interaction
    Batal, I.
    Azzi, J.
    Mounayar, M.
    Mfarrej, B.
    Abdi, R.
    LABORATORY INVESTIGATION, 2012, 92 : 396A - 396A
  • [26] The Effects of Oxidative Stress on Dendritic Cell Migration and T-Cell Interaction
    Batal, I.
    Azzi, J.
    Mounayar, M.
    Mfarrej, B.
    Abdi, R.
    MODERN PATHOLOGY, 2012, 25 : 396A - 396A
  • [27] Hypothermia induces T-cell production of immunosuppressive cytokines
    Lee, SL
    Battistella, FD
    Go, K
    JOURNAL OF SURGICAL RESEARCH, 2001, 100 (02) : 150 - 153
  • [28] IMPACT OF IMMUNOSUPPRESSIVE MOLECULES ON T-CELL METABOLIC REPROGRAMMING
    Ramos, Ana A. Fernandez
    Marchetti-Laurent, Catherine
    Poindessous, Virginie
    Antonio, Samantha
    Bortoli, Sylvie
    Loriot, Marie-Anne
    Pallet, Nicolas
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2017, 32 : 414 - 414
  • [29] The effect of immunosuppressive molecules on T-cell metabolic reprogramming
    Fernandez-Ramos, Ana A.
    Poindessous, Virginie
    Marchetti-Laurent, Catherine
    Pallet, Nicolas
    Loriot, Marie-Anne
    BIOCHIMIE, 2016, 127 : 23 - 36
  • [30] The impact of immunosuppressive drugs on the analysis of T-cell activation
    Rovira, P
    Mascarell, L
    Truffa-Bachi, P
    CURRENT MEDICINAL CHEMISTRY, 2000, 7 (07) : 673 - 692
12345