EFFECTS OF ALPRAZOLAM ON T-CELL IMMUNOSUPPRESSIVE RESPONSE TO SURGICAL STRESS IN MICE

被引：23
|
作者：
FREIREGARABAL, M [1 ]
BELMONTE, A [1 ]
ORALLO, F [1 ]
COUCEIRO, J [1 ]
NUNEZ, MJ [1 ]
机构：
[1] UNIV SANTIAGO DE COMPOSTELA, FAC MED, DEPT PHARMACOL, E-15705 SANTIAGO, SPAIN
来源：
CANCER LETTERS | 1991年 / 58卷 / 03期
关键词：
STRESS; IMMUNITY; LYMPHOCYTES-T; BLASTIC RESPONSE; ALPRAZOLAM; ANXIOLYTICS; ADRENOCORTICOTROPIC HORMONE;
D O I：
10.1016/0304-3835(91)90098-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Mice submitted to surgical stress induced by laparotomy and treated with chronic alprazolam (1 mg/kg) showed a reduction in stress-induced suppression of thymus and spleen cellularity, as well as in peripheral T lymphocyte population. The blastic response of spleen lymphoid cells was also assessed and found to partially supress the inhibitory effect of surgery.
引用
收藏
页码：183 / 187
页数：5
相关论文
共 50 条
  • [1] EFFECTS OF MIDAZOLAM ON T-CELL IMMUNOSUPPRESSIVE RESPONSE TO SURGICAL STRESS IN MICE
    FREIREGARABAL, M
    BELMONTE, A
    BALBOA, JL
    NUNEZ, MJ
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1992, 43 (01) : 85 - 89
  • [2] EFFECTS OF DIAZEPAM ON T-CELL IMMUNOSUPPRESSIVE RESPONSE TO SURGICAL STRESS IN MICE
    FREIREGARABAL, M
    BELMONTE, A
    MEIZOSO, MJ
    BALBOA, JL
    SUAREZQUINTANILLA, JA
    ACTA THERAPEUTICA, 1991, 17 (02) : 137 - 146
  • [3] EFFECTS OF ALPRAZOLAM ON CELLULAR IMMUNE-RESPONSE TO SURGICAL STRESS IN MICE
    FREIREGARABAL, M
    NUNEZ, MJ
    BALBOA, JL
    FERNANDEZRIAL, JC
    VALLEJO, LG
    GONZALEZBAHILLO, J
    REYMENDEZ, M
    CANCER LETTERS, 1993, 73 (2-3) : 155 - 160
  • [4] EFFECTS OF BUSPIRONE ON THE IMMUNOSUPPRESSIVE RESPONSE TO STRESS IN MICE
    FREIREGARABAL, M
    BELMONTE, A
    SUAREZQUINTANILLA, J
    ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, 1991, 314 : 160 - 168
  • [5] Effects of fluoxetine on the immunosuppressive response to stress in mice
    FreireGarabal, M
    Nunez, MJ
    Losada, C
    Pereiro, D
    Riveiro, MP
    GonzalezPatino, E
    Mayan, JM
    ReyMendez, M
    LIFE SCIENCES, 1997, 60 (26) : PL403 - PL413
  • [6] EFFECTS OF AMPHETAMINE ON T-CELL IMMUNE-RESPONSE IN MICE
    FREIREGARABAL, M
    BALBOA, JL
    NUNEZ, MJ
    CASTANO, MT
    LLOVO, JB
    FERNANDEZRIAL, JC
    BELMONTE, A
    LIFE SCIENCES, 1991, 49 (16) : PL107 - PL112
  • [7] Differential effects of immunosuppressive drugs on T-cell motility
    Datta, A.
    David, R.
    Glennie, S.
    Scott, D.
    Cernuda-Morollon, E.
    Lechler, R. I.
    Ridley, A. J.
    Marelli-Berg, F. M.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (12) : 2871 - 2883
  • [8] INVITRO IMMUNOSUPPRESSIVE PROPERTIES OF SPERGUALINS TO MURINE T-CELL RESPONSE
    FUJII, H
    TAKADA, T
    NEMOTO, K
    ABE, F
    FUJII, A
    TAKEUCHI, T
    JOURNAL OF ANTIBIOTICS, 1989, 42 (05): : 788 - 794
  • [9] DIFFERENTIAL EFFECTS OF IMMUNOSUPPRESSIVE DRUGS ON REGULATORY T-CELL FUNCTION
    Janssen, M. W. W.
    Mohrbach, J.
    Becker, F.
    Siemer, S.
    Stoeckle, M.
    Fliser, D.
    Sester, M. L.
    Sester, U.
    EUROPEAN UROLOGY SUPPLEMENTS, 2010, 9 (02) : 163 - 164
  • [10] Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice
    Sharma, Rahul
    Ju, Shyr-Te
    CLINICAL IMMUNOLOGY, 2010, 136 (02) : 162 - 169
12345