NEW SYNTHESIS OF 2-ARYL- AND 2-HETARYLPYRROLES FROM 1-PROPARGYLBENZOTRIAZOLE

被引：0
|
作者：
KATRITZKY, AR
LI, JQ
GORDEEV, MF
机构：
来源：
SYNTHESIS-STUTTGART | 1994年 / 01期
关键词：
ADDUCTS; FROM THE REACTANTS SHOWN; CYCLOELIMINATE TO 2-ARYL- AND 2-HETARYLPYRROLES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1-(3-Lithiopropargyl)benzotriazole reacts with N-tosylarylimines to give adducts which undergo cycloelimination on treatment with ethanolic sodium hydroxide to afford 2-aryl- and 2-hetarylpyrroles in 45-60% yields. Treatment of 1-(1,3-dilithiopropargyl)benzotriazole successively with 1 equivalent of an alkyl halide followed by N-tosyl(1-naphthyl)imine and then ethanolic sodium hydroxide gives the corresponding 5-alkyi-2-(1-naphthyl)pyrroles in 43-56% yields.
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页码：93 / 96
页数：4
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