NEW SYNTHESIS OF 2-ARYL- AND 2-HETARYLPYRROLES FROM 1-PROPARGYLBENZOTRIAZOLE

被引：0

作者：

KATRITZKY, AR

LI, JQ

GORDEEV, MF

机构：

来源：

SYNTHESIS-STUTTGART | 1994年 / 01期

关键词：

ADDUCTS; FROM THE REACTANTS SHOWN; CYCLOELIMINATE TO 2-ARYL- AND 2-HETARYLPYRROLES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-(3-Lithiopropargyl)benzotriazole reacts with N-tosylarylimines to give adducts which undergo cycloelimination on treatment with ethanolic sodium hydroxide to afford 2-aryl- and 2-hetarylpyrroles in 45-60% yields. Treatment of 1-(1,3-dilithiopropargyl)benzotriazole successively with 1 equivalent of an alkyl halide followed by N-tosyl(1-naphthyl)imine and then ethanolic sodium hydroxide gives the corresponding 5-alkyi-2-(1-naphthyl)pyrroles in 43-56% yields.

引用

页码：93 / 96

页数：4

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