Fluorine-18 patents (2009-2015). Part 1: novel radiotracers

被引：10
|
作者：
Brooks, Allen F. [1 ]
Drake, Lindsey R. [2 ]
Stewart, Megan N. [2 ]
Cary, Brian P. [1 ]
Jackson, Isaac M. [1 ]
Mallette, Dale [1 ]
Mossine, Andrew V. [1 ]
Scott, Peter J. H. [1 ,2 ]
机构：
[1] Univ Michigan, Dept Radiol, Sch Med, 1301 Catherine St, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA
来源：
PHARMACEUTICAL PATENT ANALYST | 2016年 / 5卷 / 01期
关键词：
D O I：
10.4155/ppa.15.36
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The most commonly utilized PET radionuclide is fluorine-18 (F-18) because of its convenient half-life and excellent imaging properties. In this review, we present the first analysis of patents issued for radiotracers labeled with fluorine-18 (between 2009 and 2015), and provide perspective on current trends and future directions in PET radiotracer development.
引用
收藏
页码：17 / 47
页数：31
相关论文
共 50 条
  • [31] 18F-rFDGSCH: A novel Fluorine-18 PET imaging agent for Dopamine D1 Receptors
    Baranwal, Aparna
    Mukherjee, Jogeshwar
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [32] NOVEL FLUORINE-18 LABELED ESTROGEN RECEPTOR LIGAND: FLUOROALKYL CYCLOFENIL ANALOGUES
    Seo, J. W.
    Chi, D. Y.
    Dence, C. C.
    Sharp, T. L.
    Welch, M. J.
    Katzenellenbogen, J. A.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2005, 48 : S221 - S221
  • [33] Radiolabeling with fluorine-18 of a protein, interleukin-1 receptor antagonist
    Prenant, C.
    Cawthorne, C.
    Fairclough, M.
    Rothwell, N.
    Boutin, H.
    APPLIED RADIATION AND ISOTOPES, 2010, 68 (09) : 1721 - 1727
  • [34] New fluorine-18 radiolabeled Cdk4/6 inhibitors: potential radiotracers for tumour imaging by positron emission tomography
    Graf, F.
    Koehler, L.
    Mosch, B.
    Pietzsch, J.
    EJC SUPPLEMENTS, 2009, 7 (02): : 120 - 121
  • [35] RADIOTRACERS IN FLUORINE CHEMISTRY .2. FLUORINE-18 EXCHANGE BETWEEN CARBONYL FLUORIDE AND GROUP-I FLUORIDES - EFFECT OF DIPOLAR, APROTIC-SOLVENTS
    FRASER, CJW
    SHARP, DWA
    WEBB, G
    WINFIELD, JM
    JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1974, (01): : 112 - 115
  • [36] Production of a Novel Fluorine-18 Labeled Silver Species Derived from [18F]HF
    Wright, Jay
    Brooks, Allen
    Sanford, Melanie
    Scott, Peter
    JOURNAL OF NUCLEAR MEDICINE, 2021, 62
  • [37] Investigation of Vape Devices as Novel Drug Delivery Systems Using Fluorine-18 Radiolabelling
    Herbert, George
    Woolley, Glenn
    Roberts, David
    Domarkas, Juozas
    Wright, Graham
    Archibald, Steve
    JOURNAL OF NUCLEAR MEDICINE, 2021, 62
  • [38] PET Imaging of Neurofibromatosis Type 1 with a Fluorine-18 Labeled Tryptophan Radiotracer
    Yue, Xuyi
    Stauff, Erik
    Boyapati, Shriya
    Langhans, Sigrid A.
    Xu, Wenqi
    Makrogiannis, Sokratis
    Okorie, Uchenna J.
    Okorie, Azubuike M.
    Kandula, Vinay V. R.
    Kecskemethy, Heidi H.
    Nikam, Rahul M.
    Averill, Lauren W.
    Shaffer, Thomas H.
    PHARMACEUTICALS, 2024, 17 (06)
  • [39] Improved stability of a novel fluorine-18 labeled TCO analogue for pretargeted PET imaging
    Ruivo, Eduardo
    Adhikari, Karuna
    Elvas, Filipe
    Fissers, Jens
    Vangestel, Christel
    Staelens, Steven
    Stroobants, Sigrid
    Van der Veken, Pieter
    Wyffels, Leonie
    Augustyns, Koen
    NUCLEAR MEDICINE AND BIOLOGY, 2019, 76-77 : 36 - 42
  • [40] Toward Novel [18F]Fluorine-Labeled Radiotracers for the Imaging of α-Synuclein Fibrils
    Uzuegbunam, Bright C.
    Li, Junhao
    Paslawski, Wojciech
    Weber, Wolfgang
    Svenningsson, Per
    Agren, Hans
    Yousefi, Behrooz Hooshyar
    FRONTIERS IN AGING NEUROSCIENCE, 2022, 14
12345