Fluorine-18 patents (2009-2015). Part 1: novel radiotracers

被引：10
|
作者：
Brooks, Allen F. [1 ]
Drake, Lindsey R. [2 ]
Stewart, Megan N. [2 ]
Cary, Brian P. [1 ]
Jackson, Isaac M. [1 ]
Mallette, Dale [1 ]
Mossine, Andrew V. [1 ]
Scott, Peter J. H. [1 ,2 ]
机构：
[1] Univ Michigan, Dept Radiol, Sch Med, 1301 Catherine St, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA
来源：
PHARMACEUTICAL PATENT ANALYST | 2016年 / 5卷 / 01期
关键词：
D O I：
10.4155/ppa.15.36
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The most commonly utilized PET radionuclide is fluorine-18 (F-18) because of its convenient half-life and excellent imaging properties. In this review, we present the first analysis of patents issued for radiotracers labeled with fluorine-18 (between 2009 and 2015), and provide perspective on current trends and future directions in PET radiotracer development.
引用
收藏
页码：17 / 47
页数：31
相关论文
共 50 条
  • [21] Rhenium(i) complexation-dissociation strategy for synthesising fluorine-18 labelled pyridine bidentate radiotracers
    Klenner, Mitchell A.
    Zhang, Bo
    Ciancaleoni, Gianluca
    Howard, James K.
    Maynard-Casely, Helen E.
    Clegg, Jack K.
    Massi, Massimiliano
    Fraser, Benjamin H.
    Pascali, Giancarlo
    RSC ADVANCES, 2020, 10 (15) : 8853 - 8865
  • [22] Comparative evaluation of two novel fluorine-18 PET radiotracers for the alpha7 nicotinic acetylcholine receptor (α7nAChR)
    Teodoro, Rodrigo
    Deuther-Conrad, Winnie
    Roetering, Sven
    Scheunemann, Matthias
    Patt, Marianne
    Donat, Cornelius
    Wenzel, Barbara
    Peters, Dan
    Sabri, Osama
    Brust, Peter
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [23] PYFLARE - A NOVEL METHOD FOR THE FLUORINE-18 LABELLING OF SMALL MOLECULES
    Klenner, M.
    Pascali, G.
    Zhang, B.
    Massi, M.
    Fraser, B.
    INTERNAL MEDICINE JOURNAL, 2019, 49 : 10 - 10
  • [24] A novel fluorine-18 PET radiotracer for imaging sigma-1 receptor in the brain
    Fan, Jinda
    Yu, Lihai
    Padakanti, Prashanth
    Zhou, Haiying
    Pamu, Sreedhar
    Li, Shihong
    Parsons, Stanley
    Mach, Robert
    Permutters, Joel
    Tu, Zhude
    JOURNAL OF NUCLEAR MEDICINE, 2012, 53
  • [25] Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers
    Lim, Ting Xiang
    Migotto, Mary-Anne
    Mardon, Karine
    Paterson, Brett
    Reutens, David
    NUCLEAR MEDICINE AND BIOLOGY, 2023, 126 : S174 - S175
  • [26] [18F]GP1, a novel fluorine-18 labeled tracer for PET imaging of thrombi
    Stephens, A.
    Lohrke, J.
    Siebeneicher, H.
    Berger, M.
    Bauser, M.
    Berndt, M.
    Mueller, A.
    Zerna, M.
    Friebe, M.
    Dinkelborg, L. M.
    Huetter, J.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 : S304 - S304
  • [27] [18F]GP1, a novel fluorine-18 labeled tracer for PET imaging of thrombi
    Stephens, Andrew
    Lohrke, Jessica
    Siebeneicher, Holger
    Berger, Markus
    Bauser, Marcus
    Berndt, Mathias
    Mueller, Andre
    Zerna, Marion
    Friebe, Matthias
    Huetter, Joachim
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [28] Novel Fluorine-18 Labeled Benzothiazole Derivatives for Amyloid Imaging by PET
    Furumoto, S.
    Kawauchi, T.
    Okamura, N.
    Tago, T.
    Harada, R.
    Zhang, M. R.
    Maruyama, M.
    Higuchi, M.
    Yanai, K.
    Iwata, R.
    Kudo, Y.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 : S168 - S168
  • [29] Radiosynthesis and evaluation of fluorine-18 and carbon-11 radiotracers for PET Imaging of PDE10A in colorectal cancer
    Fan, Jinda
    Yasui, Norio
    Kasten, Benjamin
    Samuel, Sharon
    Chen, Xi
    Piazza, Gary
    Luo, Zonghua
    Tu, Zhude
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [30] Development and preparation of novel carbon-11/fluorine-18 containing radiotracers for non-invasive PET-imaging of EphB4
    Mamat, Constantin
    Ebert, Kristin
    Caballero, Julio
    Pietzsch, Jens
    Steinbach, Joerg
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2013, 56 : S400 - S400
12345