CONDENSED HETEROCYCLIC LACTAMS .2. SYNTHESIS OF NEW 4-ARYLQUINOLIN-2(1H)-ONE DERIVATIVES

被引：0

作者：

HAZAI, L

DEAK, G

TOTH, G

SOHAR, P

TAMAS, J

GYORGY, L

机构：

[1] TECH UNIV BUDAPEST,INST GEN & ANALYT CHEM,H-1111 BUDAPEST,HUNGARY

[2] EGIS PHARMACEUT,DEPT SPECTROSCOP,H-1475 BUDAPEST,HUNGARY

[3] HUNGARIAN ACAD SCI,INST EXPTL MED,H-1450 BUDAPEST,HUNGARY

[4] HUNGARIAN ACAD SCI,CENT RES INST CHEM,H-1525 BUDAPEST,HUNGARY

来源：

ACTA CHIMICA HUNGARICA-MODELS IN CHEMISTRY | 1992年 / 129卷 / 02期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalytic hydrogenation of the nitro group of 4-(4-nitrophenyl)quinolin-2(1H)-one (1) gave, without saturation of the C-3 - C-4 double bond, a new representative of 4-arylquinolin-2(1H)-ones: the 4-(4-aminophenyl) derivative 3. The use of this compound as a starting material made possible the syntheses of potentially CNS active 4-alkylaminoacylamino-substituted 4-arylquinolin-2(1H)-ones (6a-d) and related compounds (6e-j).

引用

页码：269 / 275

页数：7

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