SYNTHETIC STUDIES ON BRYOSTATINS, ANTINEOPLASTIC METABOLITES - CONVERGENT SYNTHESIS OF THE C1-C16 FRAGMENT SHARED BY ALL OF THE BRYOSTATIN FAMILY

被引：34

作者：

OHMORI, K ^{[1
]}

SUZUKI, T ^{[1
]}

MIYAZAWA, K ^{[1
]}

NISHIYAMA, S ^{[1
]}

YAMAMURA, S ^{[1
]}

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT CHEM,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 31期

关键词：

BRYOSTATINS; BUGULA-NERITINA LINNEAUS; AMATHIA-CONVOLUTA; ANTINEOPLASTIC ACTIVITY;

D O I：

10.1016/S0040-4039(00)74063-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C1-C-16 fragment of bryostatins could successfully be synthesized by tandem connection of the appropriate three fragments and effective introduCtion of the alpha,beta-unsaturated esters at the C-13 position.

引用

页码：4981 / 4984

页数：4

共 50 条

[41] Formal Synthesis of the Bryostatin Northern Hemisphere: Asymmetric Synthesis of the B Ring and C1-C9 Fragment
Nakagawa-Goto, Kyoko
Crimmins, Michael T.
SYNLETT, 2011, (10) : 1413 - 1418
[42] ORGN 691-Synthetic studies on tedanolide C: Versatile synthesis of the C1-C12 fragment
Smith, Thomas E.
Fink, Sarah J.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
[43] Total Syntheses of Bryostatins: Synthesis of Two Ring-Expanded Bryostatin Analogues and the Development of a New-Generation Strategy to Access the C7-C27 Fragment
Trost, Barry M.
Yang, Hanbiao
Dong, Guangbin
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (35) : 9789 - 9805
[44] Synthetic Studies on Tedanolide: Stereoselective Synthesis of the C13-C21 Fragment
Park, Su Ho
Min, Jae Ki
Park, Se Hwan
Lee, Hyo Won
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2009, 30 (03): : 537 - 538
[45] Synthetic studies on mycalolide B: Synthesis of the C7-C35 fragment
Kimura, Tomoyuki
Kuribayashi, Satomi
Sengoku, Tetsuya
Matsui, Keita
Ueda, Shoko
Hayakawa, Ichiro
Suenaga, Kiyotake
Kigoshi, Hideo
CHEMISTRY LETTERS, 2007, 36 (12) : 1490 - 1491
[46] Synthetic studies on tedanolide: Stereoselective synthesis of the C13-C21 fragment
Park, Su Ho
Min, Jae Ki
Park, Se Hwan
Lee, Hyo Won
Bulletin of the Korean Chemical Society, 2009, 30 (03) : 537 - 538
[47] Synthetic studies of HIV-active Didemnaketal A analogue - Synthesis of a C1-C7 fragment
Jia, YX
Wang, PZ
Wu, B
Tu, YQ
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2000, 21 (05): : 729 - 730
[48] SYNTHETIC STUDIES ON MACROLIDES .1. STEREOSPECIFIC SYNTHESIS OF 9-C-11-C FRAGMENT OF METHYNOLIDE
SHIYONOK, AI
SVIRIDOV, AF
CHIZHOV, OS
BIOORGANICHESKAYA KHIMIYA, 1977, 3 (07): : 914 - 919
[49] Synthetic studies toward amphidinolide B1:: Synthesis of the C9-C26 fragment
Zhang, W
Carter, RG
ORGANIC LETTERS, 2005, 7 (19) : 4209 - 4212
[50] Studies on the total synthesis of formamicin: Synthesis of the C(1)-C(11) fragment
Powell, NA
Roush, WR
ORGANIC LETTERS, 2001, 3 (03) : 453 - 456

← 1 2 3 4 5 →