SYNTHETIC STUDIES ON BRYOSTATINS, ANTINEOPLASTIC METABOLITES - CONVERGENT SYNTHESIS OF THE C1-C16 FRAGMENT SHARED BY ALL OF THE BRYOSTATIN FAMILY

被引：34

作者：

OHMORI, K ^{[1
]}

SUZUKI, T ^{[1
]}

MIYAZAWA, K ^{[1
]}

NISHIYAMA, S ^{[1
]}

YAMAMURA, S ^{[1
]}

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT CHEM,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 31期

关键词：

BRYOSTATINS; BUGULA-NERITINA LINNEAUS; AMATHIA-CONVOLUTA; ANTINEOPLASTIC ACTIVITY;

D O I：

10.1016/S0040-4039(00)74063-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C1-C-16 fragment of bryostatins could successfully be synthesized by tandem connection of the appropriate three fragments and effective introduCtion of the alpha,beta-unsaturated esters at the C-13 position.

引用

页码：4981 / 4984

页数：4

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