- Fabrication of Porous beta-TCP Bone Graft Substitutes Using PMMA Powder and their Biocompatibility Study

被引：4
|
作者：
Song, Ho-Yeon [1 ]
Youn, Min-Ho [3 ]
Kim, Young-Hee [1 ]
Min, Young-Ki [2 ]
Yang, Hun-Mo [2 ]
Lee, Byong-Taek [3 ]
机构：
[1] Soonchunhyang Univ, Sch Med, Cheonan 330090, Chungnam, South Korea
[2] Soonchunhyang Univ, Sch Med, Dept Physiol, Cheonan 330090, Chungnam, South Korea
[3] Soonchunhyang Univ, Sch Med, Dept Biomed Engn & Mat, 366-1 Ssangyoung Dong, Cheonan 330090, Chungnam, South Korea
来源：
KOREAN JOURNAL OF MATERIALS RESEARCH | 2007年 / 17卷 / 06期
关键词：
bone graft substitute; beta-TCP; porous body; biocompatibility;
D O I：
10.3740/MRSK.2007.17.6.318
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Porous beta-tricakium phosphate (13-TCP) bioceramic was fabricated by pressureless sintering using commercial HAp and different volume percentages of PMMA powders (30-60 vol.%). The range of spherical pore size was about 200-250 mu m in diameter. By increasing the PMMA content, the number of pores and their morphology were dramatically changed as well as decreased the material properties. In case of using 60 vol.% PMMA content, network-type pores were found, due to the necking of the PMMA powders. The values of relative density, elastic modulus, bending strength and hardness of the 60 vol.% PMMA content sample, sintered at 1500 degrees C, were about 46%, 22.2 GPa, 5 MPa and 182 Hv respectively. Human osteoblast-like MG-63 cells and osteoclast-like Raw 264.7 cells were well grown and fully covered all of the porous beta-TCP bodies sintered at 1500 degrees C.
引用
收藏
页码：318 / 322
页数：5
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