Synthesis and biological studies of novel 2-(4-substitutedbenzylthio)-5-amino-6-(benzo[d] thiazol-2-yl)-7-(4-chlorophenyl)pyrido-[2,3-d]-pyrimidin-4(3H)-one derivatives

被引：0

作者：

Suresh, M. ^{[1
]}

Lavanya, P. ^{[2
]}

Raju, K. Naga ^{[2
]}

Jonnalagadda, Sreekanth B. ^{[1
]}

Rao, C. Venkata ^{[2
]}

机构：

[1] Univ KwaZulu Natal, Sch Chem, ZA-4000 Durban, South Africa

[2] Sri Venkateswara Univ, Coll Sci, Dept Chem, Tirupati 517502, Andhra Prades, India

来源：

ORGANIC COMMUNICATIONS | 2011年 / 4卷 / 02期

关键词：

2-(4-substitutedbenzylthio)-5-amino-6-(benzo[d] thiazol-2-yl)-7-(4-chlorophenyl)pyrido[2,3-d]-pyrimidin-4(3H)-one; antibacterial; antifungal;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel 2-(4-substitutedbenzylthio)-5-amino-6-(benzo[d]thiazol-2-yl)-7-(4-chlorophenyl) pyrido[2,3-d]pyrimidin-4(3H)-one derivatives were synthesized and evaluated for their antibacterial and antifungal activity. All the derivatives were efficiently synthesized in four steps. The structure of the newly synthesized compounds was elucidated by their IR, H-1-NMR, C-13 NMR, LCMS mass spectra and elemental analysis.

引用

页码：33 / 41

页数：9

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