RELATIONSHIP OF METHOTREXATE TOXICITY TO ITS PHARMACOKINETICS AND TO GASTROINTESTINAL CELL KINETICS IN MOUSE

被引:0
|
作者
ZAHARKO, DS
JOHNS, DG
机构
来源
PHARMACOLOGIST | 1971年 / 13卷 / 02期
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:260 / &
相关论文
共 50 条
  • [41] EVALUATION OF 24-HOUR INFUSION OF HIGH-DOSE METHOTREXATE - PHARMACOKINETICS AND TOXICITY
    GOH, TS
    WONG, KY
    LAMPKIN, B
    OLEARY, J
    GNARRA, D
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1979, 3 (03) : 177 - 180
  • [42] PHARMACOKINETICS AND TOXICITY OF METHOTREXATE IN CHILDREN WITH DOWN-SYNDROME AND ACUTE LYMPHOCYTIC-LEUKEMIA
    GARRE, ML
    RELLING, MV
    KALWINSKY, D
    DODGE, R
    CROM, WR
    ABROMOWITCH, M
    PUI, CH
    EVANS, WE
    JOURNAL OF PEDIATRICS, 1987, 111 (04): : 606 - 612
  • [43] Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats
    Yokooji, Tomoharu
    Mori, Nobuhiro
    Murakami, Teruo
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2011, 63 (02) : 206 - 213
  • [44] The effects of genetic polymorphism on toxicity and pharmacokinetics of methotrexate in Egyptian adult patients with leukaemia or lymphoma
    Shendy, Khloud
    Abdelkawy, Khaled
    Ali, Ahmed Amin
    Belal, Fathalla
    Abdelhakiem, Mostafa
    Magdy, Galal
    Anber, Nahla
    Elbarbry, Fawzy
    XENOBIOTICA, 2024, 54 (02) : 95 - 105
  • [45] Pharmacokinetics of Para-Aminosalicylic Acid and Its 2 Major Metabolites: A Potential Relationship to the Development of Gastrointestinal Intolerance
    Adams, Kim T.
    Donald, Peter R.
    Abulfathi, Ahmed A.
    Diacon, Andreas H.
    Stander, Marietjie A.
    Reuter, Helmuth
    JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 60 (04): : 489 - 494
  • [46] CIRCADIAN CHANGES IN MITOXANTRONE TOXICITY IN MICE - RELATIONSHIP WITH PLASMA PHARMACOKINETICS
    LEVI, F
    TAMPELLINI, M
    METZGER, G
    BIZI, E
    LEMAIGRE, G
    HALLEK, M
    INTERNATIONAL JOURNAL OF CANCER, 1994, 59 (04) : 543 - 547
  • [47] Cadmium toxicity and its relationship with disturbances in the cytoskeleton, cell cycle and chromosome stability
    Daniel Pizzaia
    Marina Lima Nogueira
    Mateus Mondin
    Marcia Eugenia Amaral Carvalho
    Fernando Angelo Piotto
    Millor Fernandes Rosario
    Ricardo Antunes Azevedo
    Ecotoxicology, 2019, 28 : 1046 - 1055
  • [48] Population pharmacokinetics of cyclosporine and study of the relationship between its exposure and renal toxicity during the first weeks after allogeneic hematopoietic stem cell transplantation
    Nolain, P.
    Woillard, J. B.
    Turlure, P.
    Saint-Marcoux, F.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2015, 29 : 22 - 22
  • [49] Cadmium toxicity and its relationship with disturbances in the cytoskeleton, cell cycle and chromosome stability
    Pizzaia, Daniel
    Nogueira, Marina Lima
    Mondin, Mateus
    Amaral Carvalho, Marcia Eugenia
    Piotto, Fernando Angelo
    Rosario, Millor Fernandes
    Azevedo, Ricardo Antunes
    ECOTOXICOLOGY, 2019, 28 (09) : 1046 - 1055
  • [50] Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics
    Dai, Shu
    Wang, Cheng
    Zhao, XingTao
    Ma, Cheng
    Fu, Ke
    Liu, Yanfang
    Peng, Cheng
    Li, Yunxia
    PHARMACOLOGICAL RESEARCH, 2023, 187