Immunological parameters as a new lead in the diagnosis of ovarian cancer

被引：0

作者：

Baert, T. ^{[1
,2
]}

Timmerman, D. ^{[1
,3
]}

Vergote, I. ^{[1
,2
]}

Coosemans, A. ^{[1
,2
]}

机构：

[1] UZ Leuven, Gynaecol & Obstet, B-3000 Leuven, Belgium

[2] Katholieke Univ Leuven, Dept Oncol, Leuven Canc Inst, B-3000 Leuven, Belgium

[3] Katholieke Univ Leuven, Dept Dev & Regenerat, B-3000 Leuven, Belgium

来源：

FACTS VIEWS AND VISION IN OBGYN | 2015年 / 7卷 / 01期

基金：

比利时弗兰德研究基金会;

关键词：

Ovarian cancer; diagnosis; prognostic marker; immunosuppression; regulatory T cell; myeloid derived suppressor cells; tumor-associated macrophages;

D O I：

暂无

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ovarian cancer is the leading cause of pelvic gynecological cancer death in Europe. Prognosis is poor in women diagnosed at stage III to IV or in case disease recurs. Platin-based chemotherapy and radical surgery have already improved prognosis significantly. Novel strategies in the treatment of ovarian cancer are being searched for. The study of the immune system as a valuable parameter in the development of ovarian cancer has been neglected for a long time. Nevertheless, this is a field in full progression and might open new perspectives in the diagnosis and prognosis of ovarian cancer patients and could lead to a more motivated choice of targeted therapies.

引用

页码：67 / 72

页数：6

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