HECK REACTIONS IN SOLID-PHASE SYNTHESIS

被引:93
|
作者
YU, KL
DESHPANDE, MS
VYAS, DM
机构
[1] Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, CT 06492
关键词
D O I
10.1016/0040-4039(94)88389-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Heck reactions of polymer bound aryl iodide (I) or styrene (2) with olefins or aryl halides generally gave good yields of products of high purity. The methodology developed can be applied as a convenient procedure for generating 1,2-disubstituted olefins in combinatorial chemical libraries.
引用
收藏
页码:8919 / 8922
页数:4
相关论文
共 50 条