Santolindiacetylene, a polyacetylene derivative isolated from the essential oil of Santolina canescens

被引：14
|
作者：
Utrilla, MP
Navarro, MC
Jimenez, J
Montilla, MP
Martin, A
机构：
[1] Department of Pharmacology, Faculty of Pharmacy, University of Granada
来源：
JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 11期
关键词：
D O I：
10.1021/np50125a018
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The yield, composition, and some pharmacological activities (hepatoprotective and antioxidant) of the essential oil of Santolina canescens aerial parts have been investigated. The essential oil qualitative data were determined by gc and gc-ms. The main component, santolindiacetylene [1], was isolated and characterized by spectral methods, and the structure assigned as 1-(2'-naphthyl)hexa-2,4-diyne. The protective activities of the essential oil and its main component [1] were evaluated against carbon tetrachloride-induced hepatotoxicity in a rat model. In both cases a significant hepatoprotective effect Tvas observed, as evident from the strong decrease of elevated GPT serum levels caused by carbon tetrachloride-induced hepatic damage.
引用
收藏
页码：1749 / 1752
页数：4
相关论文
共 50 条
  • [31] Essential Oil from Leaves of Lantana canescens and L. lopez-palacii Grown in Colombia
    Peralta-Bohorquez, Andres F.
    Quijano-Celis, Clara
    Gaviria, Mauricio
    Vanegas-Lopez, Consuelo
    Pino, Jorge A.
    NATURAL PRODUCT COMMUNICATIONS, 2011, 6 (02) : 247 - 249
  • [32] Effects of Santolina chamaecyparissus essential oil on rheological, thermal and antioxidative properties of dark chocolate
    Bolek, Sibel
    Tosya, Feyza
    Akcura, Sevim
    INTERNATIONAL JOURNAL OF GASTRONOMY AND FOOD SCIENCE, 2022, 27
  • [33] Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens
    Gholivand, Mohammad Bagher
    Rahimi-Nasrabadi, Mehdi
    Batooli, Hossein
    Ebrahimabadi, Abdolrasoul H.
    FOOD AND CHEMICAL TOXICOLOGY, 2010, 48 (01) : 24 - 28
  • [34] A new bisabolene derivative from the essential oil of Prangos uechtritzii fruits
    Baser, KHC
    Demirci, B
    Demirci, F
    Bedir, E
    Weyerstahl, P
    Marschall, H
    Duman, H
    Aytac, Z
    Hamann, MT
    PLANTA MEDICA, 2000, 66 (07) : 674 - 677
  • [35] Composition, irregular terpenoids, chemical variability and antibacterial activity of the essential oil from Santolina corsica Jordan et Fourr
    Liu, Kai
    Rossi, Paul-Georges
    Ferrari, Bernard
    Berti, Liliane
    Casanova, Joseph
    Tomi, Felix
    PHYTOCHEMISTRY, 2007, 68 (12) : 1698 - 1705
  • [36] Supercritical fluid extraction of the volatile oil from Santolina chamaecyparissus
    Grosso, Clara
    Figueiredo, Ana Cristina
    Burillo, Jesus
    Mainar, Ana M.
    Urieta, Jose S.
    Barroso, Jose G.
    Coelho, Jose A.
    Palavra, Antonio M. F.
    JOURNAL OF SEPARATION SCIENCE, 2009, 32 (18) : 3215 - 3222
  • [37] MONOTERPENE COMPOUNDS OF ESSENTIAL OILS FROM PLANTS OF SANTOLINA-SPECIES
    USHAKOV, VA
    MURAVEVA, DA
    BAKINA, LA
    KHIMIYA PRIRODNYKH SOEDINENII, 1976, (05): : 664 - 664
  • [38] A New Monoterpene Isolated from Nigella saliva Essential Oil
    Benharref, Ahmed
    Fdil, Rabia
    El Hanbali, Fadwa
    Zeroual, Abdellah
    Dakir, Mohamed
    Mazoir, Noureddine
    NATURAL PRODUCT COMMUNICATIONS, 2017, 12 (06) : 881 - 882
  • [39] Liposome-incorporated Santolina insularis essential oil:: Preparation, characterization and in vitro antiviral activity
    Valenti, D
    De Logu, A
    Loy, G
    Sinico, C
    Bonsignore, L
    Cottiglia, F
    Garau, D
    Fadda, AM
    JOURNAL OF LIPOSOME RESEARCH, 2001, 11 (01) : 73 - 90
  • [40] α-Bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin
    Tsai, Ying-Chieh
    Hsu, Hui-Chun
    Yang, Wen-Chia
    Tsai, Wei-Jern
    Chen, Chien-Chih
    Watanabe, Takashi
    FITOTERAPIA, 2007, 78 (01) : 7 - 11
12345