MATERNAL PERINATAL HIV-I TRANSMISSION

被引:0
|
作者
SULEODU, AO
机构
[1] Department of Obstetrics and Gynaecology, Obafemi Awolowo College of Health Sciences, Ogun State University, Sagamu, Ogun State
关键词
VERTICAL TRANSMISSION; HIV-I AND HIV-II; PERINATAL; NONSPECIFIC SYMPTOMS; FAILURE TO THRIVE; MORBIDITY AND MORTALITY;
D O I
10.1016/0020-7292(93)90223-J
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Human immunodeficiency virus, which causes acquired immunodeficiency syndrome can be transmitted vertically from mother to child and is associated with high morbidity and mortality in infants and children. A case of a mother transmitting the virus in-utero to the fetus is presented. The woman had a preterm emergency lower segment cesarean delivery and was transfused with 500 ml of HIV screened blood intraoperatively and another 3.5 l while in hospitaL The child, early in life presented with features suggestive of acquired immunodeficiency syndrome. This prompted us to investigate the child and the parents for HIV infection. The mother tested positive to HIV I and II, the child to HIV I, while the father tested negative by ELISA and Western blot methods. This is the only recorded case of infant HIV infection since the inception of this hospital in 1986 with 7504 total deliveries, even though we believe the incidence would definitely be higher, if all the infants delivered here were screened for HIV infection.
引用
收藏
页码:265 / 267
页数:3
相关论文
共 50 条
  • [31] MULTIPLE MATERNAL HIV-1 GENOTYPES IN INFANTS INFECTED BY PERINATAL TRANSMISSION
    GOODENOW, MM
    SLEASMAN, JW
    LAMERS, SL
    BARRETT, DJ
    CLINICAL RESEARCH, 1993, 41 (02): : A261 - A261
  • [32] The effect of maternal viral load on the risk of perinatal transmission of HIV-1
    Thea, DM
    Steketee, RW
    Pliner, V
    Bornschlegel, K
    Brown, T
    Orloff, S
    Matheson, PB
    Abrams, EJ
    Bamji, M
    Lambert, G
    Schoenbaum, EA
    Thomas, PA
    Heagarty, M
    Kalish, ML
    Beatrice, ST
    Chiasson, MA
    DeBernado, E
    Hutchison, S
    McVeigh, K
    Oleszko, W
    Punsalang, A
    Alford, T
    Betre, A
    Cappelli, M
    Carrasquillio, N
    Cruz, N
    Floyd, J
    FoyeSousou, V
    Jessop, DJ
    Macias, L
    Ng, D
    Nelson, K
    Rios, J
    Rosenbluth, L
    Hodge, R
    Tadros, H
    Weedon, J
    Young, S
    Zhang, ZR
    Courtland, R
    Daligadu, M
    Hoover, W
    Lopez, D
    Pollack, H
    Krasinski, K
    Belmore, A
    Champion, S
    Freedland, C
    Lovich, S
    Prince, P
    AIDS, 1997, 11 (04) : 437 - 444
  • [33] Effect of zidovudine on perinatal HIV-1 transmission and maternal viral load
    Golden, B
    Cooper, E
    Cundall, D
    Moy, R
    LANCET, 1999, 354 (9173): : 158 - 159
  • [34] MATERNAL VIRAL LOAD AS A RISK FACTOR FOR PERINATAL HIV-1 TRANSMISSION
    KRASINSKI, K
    CAO, YZ
    HO, D
    BORKOWSKY, W
    CLINICAL RESEARCH, 1992, 40 (02): : A380 - A380
  • [35] Neurological aspects of HIV-I infection in children
    Poneprasert, B
    6TH ASIAN AND OCEANIAN CONGRESS OF CHILD NEUROLOGY, 1999, : 65 - 73
  • [36] THE HIV-I NEF GENE-PRODUCT
    HARRIS, M
    TALBOT, S
    PATSILINACOS, P
    NEIL, JC
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1992, 20 (02) : 517 - 520
  • [37] HIV-I Tat: A polypeptide for all seasons
    Rubartelli, A
    Poggi, A
    Sitia, R
    Zocchi, MR
    IMMUNOLOGY TODAY, 1998, 19 (12): : 543 - 545
  • [38] HIV-I Vif, APOBEC, and intrinsic immunity
    Goila-Gaur, Ritu
    Strebel, Klaus
    RETROVIROLOGY, 2008, 5 (1)
  • [39] CHROMATIN STRUCTURE OF THE INTEGRATED HIV-I GENOME
    STANFIELDOAKLEY, S
    BRIOT, A
    CAVALLO, R
    CAVALLO, L
    ULM, SSJ
    WANG, YH
    GRIFFITH, J
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1995, 11 : S88 - S88
  • [40] HIV-I protease - Cloning, expression, and purification
    Dergousova, NI
    Amerik, AY
    Volynskaya, AM
    Rumsh, LD
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 1996, 61 (1-2) : 97 - 107