MATERNAL PERINATAL HIV-I TRANSMISSION

被引:0
|
作者
SULEODU, AO
机构
[1] Department of Obstetrics and Gynaecology, Obafemi Awolowo College of Health Sciences, Ogun State University, Sagamu, Ogun State
关键词
VERTICAL TRANSMISSION; HIV-I AND HIV-II; PERINATAL; NONSPECIFIC SYMPTOMS; FAILURE TO THRIVE; MORBIDITY AND MORTALITY;
D O I
10.1016/0020-7292(93)90223-J
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Human immunodeficiency virus, which causes acquired immunodeficiency syndrome can be transmitted vertically from mother to child and is associated with high morbidity and mortality in infants and children. A case of a mother transmitting the virus in-utero to the fetus is presented. The woman had a preterm emergency lower segment cesarean delivery and was transfused with 500 ml of HIV screened blood intraoperatively and another 3.5 l while in hospitaL The child, early in life presented with features suggestive of acquired immunodeficiency syndrome. This prompted us to investigate the child and the parents for HIV infection. The mother tested positive to HIV I and II, the child to HIV I, while the father tested negative by ELISA and Western blot methods. This is the only recorded case of infant HIV infection since the inception of this hospital in 1986 with 7504 total deliveries, even though we believe the incidence would definitely be higher, if all the infants delivered here were screened for HIV infection.
引用
收藏
页码:265 / 267
页数:3
相关论文
共 50 条
  • [1] PERINATAL TRANSMISSION OF HIV-I IN ZAMBIA
    HIRA, SK
    KAMANGA, J
    BHAT, GJ
    MWALE, C
    TEMBO, G
    LUO, N
    PERINE, PL
    BRITISH MEDICAL JOURNAL, 1989, 299 (6710): : 1250 - 1252
  • [2] Adaptive evolution in perinatal HIV-I
    Pillay, T
    Phillips, RE
    BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2005, 19 (02) : 211 - 229
  • [3] HLA-G DNA sequence variants and risk of perinatal HIV-I transmission
    Aikhionbare F.O.
    Kumaresan K.
    Shamsa F.
    Bond V.C.
    AIDS Research and Therapy, 3 (1)
  • [4] Characterization of HIV-I envelope gp4I genetic diversity and functional domains following perinatal transmission
    Ramakrishnan, Rajesh
    Mehta, Roshni
    Sundaravaradan, Vasudha
    Davis, Tiffany
    Ahmad, Nafees
    RETROVIROLOGY, 2006, 3 (1)
  • [5] Maternal malaria and perinatal HIV transmission, western Kenya
    Ayisi, JG
    van Eijk, AM
    Newman, RD
    ter Kuile, FO
    Shi, YP
    Yang, CF
    Kolczak, MS
    Otieno, JA
    Misore, AO
    Kager, PA
    Lal, RB
    Steketee, RW
    Nahlen, BL
    EMERGING INFECTIOUS DISEASES, 2004, 10 (04) : 643 - 652
  • [6] Phosphorylation of HIV-I Tat by CDK2 in HIV-I transcription
    Ammosova, Tatyana
    Berro, Reem
    Jerebtsova, Marina
    Jackson, Angela
    Charles, Sharroya
    Klase, Zachary
    Southerland, William
    Gordeuk, Victor R.
    Kashanchi, Fatah
    Nekhai, Sergei
    RETROVIROLOGY, 2006, 3 (1)
  • [7] TRANSMISSION OF HIV-I FROM MEN TO WOMEN IN CENTRAL-AFRICA
    BELEC, L
    GEORGES, AJ
    BROGAN, T
    STEENMAN, G
    GEORGESCOURBOT, MC
    MARTIN, PMV
    GENITOURINARY MEDICINE, 1989, 65 (01): : 61 - 62
  • [8] Cytopathic mechanisms of HIV-I
    Costin, Joshua M.
    VIROLOGY JOURNAL, 2007, 4
  • [9] Dealing with HIV-I diversity
    Rosario, M.
    Borthwick, N.
    Bridgeman, A.
    Watkins, D.
    Colloca, S.
    Quakkelaar, E. D.
    Liljestrom, P.
    Nicosia, A.
    Melief, C. J.
    Hanke, T.
    RETROVIROLOGY, 2009, 6
  • [10] MECHANISMS OF PATHOGENESIS OF HIV-I
    WAINBERG, MA
    ROY, S
    ROOKE, R
    TREMBLAY, M
    TUMOR BIOLOGY, 1987, 8 (06) : 286 - 287