HODGKINS-DISEASE IN CHILDREN

This study provides information about histological types of Hodgkin's disease (HD) among children of Pakistan. Hodgkins disease constitutes 12 per cent of all pediatric malignant tumours. The peak incidence is between 6 and 10 years. The male to female ratio is 5.25:1. The majority (78 per cent) present with cervical lymphadenopathy. Mixed cellularity (MC) is the commonest histological type. In the developed countries nodular sclerosis (NS) and lymphocyte predominant (LP) subtypes are more common, and which have better prognosis. The developing countries have a higher incidence of poor prognostic subtypes. Our study indicates a situation intermediate between the two.