LONGEVITY OF RABIES ANTIBODY TITER IN RECIPIENTS OF HUMAN-DIPLOID CELL RABIES VACCINE

被引：38
|
作者：
BRIGGS, DJ [1 ]
SCHWENKE, JR [1 ]
机构：
[1] KANSAS STATE UNIV AGR & APPL SCI,DEPT STAT,MANHATTAN,KS 66506
来源：
VACCINE | 1992年 / 10卷 / 02期
关键词：
RABIES; VACCINE; INTRAMUSCULAR; INTRADERMAL; LONGEVITY;
D O I：
10.1016/0264-410X(92)90029-J
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Sera from individuals across the USA and Peace Corps Volunteers (PCV) were assayed for neutralizing antibody to human diploid cell rabies vaccine (HDCV). A pairwise comparison between intramuscular (i.m.) and intradermal (i.d.) administration, PCV and non-PCV, revealed statistically significant differences between i.m. and i.d. for PCV and non-PCV, and between PCV and non-PCV for i.d. and i.m. administration. Survival analysis and frequency tables employing chi(2) tests determined that the percentage probability of maintaining an adequate titre from 1.5-2.0 years after primary vaccination was 99% in non-PCV i.m., 93% in non-PCV i.d., 88% in PCV i.m., and 64% in PCV i.d.
引用
收藏
页码：125 / 129
页数：5
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