We report on a 67-year-old female patient with characteristic clinical and histological features of postmenopausal frontal fibrosing alopecia (PFFA). PFFA, first described by Kossard in 1994, is a rare condition that predominantly occurs in postmenopausal women developing a fibrosing bandlike alopecia associated with progressive recession of the frontoparietal hairline and loss of the eyebrows. Histological features consisting of perifollicular lymphocytic infiltrates and concentric fibrosis around the isthmus and infundibular region are identical with those of lichen planopilaris. PFFA cannot unequivocally be distinguished from other fibrosing disorders such as lichen planopilaris or ulerythema ophryogenes. Management (e.g. glucocorticoids, retinoids or chloroquin) is usually unsatisfactory, particularly in the fibrosing stage of disease.
机构:
Sapporo Med Univ, Dept Dermatol, Sapporo, Hokkaido, Japan
Sapporo Kosei Gen Hosp, Sapporo, Hokkaido, JapanKojinkai Sapporo Dermatol Clin, Chyuo Ku, Sapporo, Hokkaido 0600063, Japan
Sato, Makito
Saga, Kenji
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机构:
Kojinkai Sapporo Dermatol Clin, Chyuo Ku, Sapporo, Hokkaido 0600063, JapanKojinkai Sapporo Dermatol Clin, Chyuo Ku, Sapporo, Hokkaido 0600063, Japan
Saga, Kenji
Takahashi, Hiroyuki
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机构:
Sapporo Kosei Gen Hosp, Sapporo, Hokkaido, JapanKojinkai Sapporo Dermatol Clin, Chyuo Ku, Sapporo, Hokkaido 0600063, Japan
Takahashi, Hiroyuki
JOURNAL OF DERMATOLOGY,
2008,
35
(11):
: 729
-
731
机构:
Univ KwaZulu Natal, Dept Dermatol, ZA-4008 Durban, Kwa Zulu Natal, South AfricaUniv KwaZulu Natal, Dept Dermatol, ZA-4008 Durban, Kwa Zulu Natal, South Africa
Dlova, N.
Goh, C-L
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机构:
Natl Skin Ctr, Dept Dermatol, Singapore, SingaporeUniv KwaZulu Natal, Dept Dermatol, ZA-4008 Durban, Kwa Zulu Natal, South Africa
Goh, C-L
Tosti, A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USAUniv KwaZulu Natal, Dept Dermatol, ZA-4008 Durban, Kwa Zulu Natal, South Africa