EFFECT OF BUCKWHEAT EXTRACT ON FREE-RADICAL GENERATION IN RABBITS ADMINISTERED HIGH-FAT DIET

被引：21
|
作者：
WOJCICKI, J [1 ]
SAMOCHOWIEC, L [1 ]
GONET, B [1 ]
JUZWIAK, S [1 ]
DABROWSKAZAMOJCIN, E [1 ]
KATDONSKA, M [1 ]
TUSTANOWSKI, S [1 ]
机构：
[1] POMERANIAN MED ACAD,DEPT RADIOISOTOPES,PL-70111 SZCZECIN,POLAND
来源：
PHYTOTHERAPY RESEARCH | 1995年 / 9卷 / 05期
关键词：
EXPERIMENTAL HYPERLIPEMIA; HIGH-FAT DIET FED RABBITS; FREE RADICAL GENERATION; BUCKWHEAT EXTRACT;
D O I：
10.1002/ptr.2650090503
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In this study the effect of buckwheat extract (BE) on the level of malondialdehyde (MDA), lipids and hormones, and on the concentration of ascorbate free radicals in the liver (compared with rutin) in animals receiving a high-fat diet (HFD) was measured. Mate mongrel rabbits were randomly divided into four groups: (1) control, (2) animals given HFD containing cholesterol and coconut oil, (3) rabbits treated with HFD + BE, (4) HFD + rutin, over a period of 12 weeks. The concentration of MDA in rabbits of group 3 (HFD+BE) was slightly but significantly decreased, whilst the number of ascorbate free radicals, examined in vitro, in the liver was markedly elevated. The level of testosterone in rabbit blood serum (group 3) was increased, but the insulin concentration was significantly diminished (in comparison with group 2). The content of total cholesterol and triglyceride in the liver of animals maintained on BE was decreased. Quite distinct superiority of BE, compared with rutin, was shown.
引用
收藏
页码：323 / 326
页数：4
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