CALCULATION OF KINETIC-PARAMETERS OF A REVERSIBLE ENZYMATIC-REACTION IN STATES OF MAXIMAL ACTIVITY

被引：0
|
作者：
HEINRICH, R [1 ]
HOFFMANN, E [1 ]
HOLZHUTTER, HG [1 ]
机构：
[1] HUMBOLDT UNIV,BEREICH MED CHARITE,INST BIOCHEM,O-1040 BERLIN,GERMANY
来源：
BIOMEDICA BIOCHIMICA ACTA | 1990年 / 49卷 / 8-9期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Optimal values of the rate constants of a reversible enzymatic reaction are calculated by maximizing the enzymatic activity. The results depend on the substrate and product concentrations. Expressions for optimal maximal activities are derived and conclusions are drawn for the optimal ratios of substrate concentrations and Michaelis-constants.
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页码：891 / 902
页数：12
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