Under acidic conditions, Hantzsch-type 4-antipyryl-1,4-dihydropyridines undergo an elimination of the 4-substituent to yield 4-unsubstituted pyridines and antipyrine. The mechanism and the scope of the reaction are discussed.
机构:
Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R ChinaLanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
Chen, Zong Yuan
Zhang, Wei
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机构:
Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R ChinaLanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China