MACROCYCLIC TRICHOTHECENES FROM BRAZILIAN BACCHARIS SPECIES - FROM MICROANALYSIS TO LARGE-SCALE ISOLATION

被引：22

作者：

JARVIS, BB

机构：

[1] Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland

来源：

PHYTOCHEMICAL ANALYSIS | 1992年 / 3卷 / 06期

关键词：

COUNTERCURRENT CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLYETHYLENEIMINE SILICA; RORIDINS; TRICHOVERRINS; BACCHARINOIDS; SEPARATION METHODS;

D O I：

10.1002/pca.2800030602

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Two Brazilian species of Baccharis, B. megapotamica and B. coridifolia have been shown to contain a number of macrocyclic trichothecene antibiotics some of which are identical to those produced by the common soil fungi Myrothecium. A number of different materials and methods have been used in a large-scale (1800 kg) isolation procedure and in the chemical analysis of plant material, inter alia ferric gel precipitation, fractionation using polyethyleneimine impregnated silica gel and countercurrent chromatography.

引用

页码：241 / 249

页数：9

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