APPLICATION OF THE FOLIN-CIOCALTEAU REAGENT TO THE DETERMINATION OF SALBUTAMOL IN PHARMACEUTICAL PREPARATIONS

被引：21
|
作者：
SADLER, NP
JACOBS, H
机构：
[1] Department of Chemistry, University of the West Indies, Mona
来源：
TALANTA | 1995年 / 42卷 / 10期
关键词：
D O I：
10.1016/0039-9140(95)01534-I
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A method for the determination of salbutamol in both tablets and syrups is described. It utilizes the reduction of the Folin-Ciocalteau reagent by the phenolic group, monitoring the absorbance of the resulting complex at 760 nm. Results obtained are linear over the range 0-6 mu g ml(-1) salbutamol. Coloring material was removed by anionexchange chromatography prior to analysis and there was no interference from sucrose, neutral flavorings or the common preservative sodium benzoate. This method appears suitable as a general assay for salbutamol.
引用
收藏
页码：1385 / 1388
页数：4
相关论文
共 50 条
12345