IMAGING OF OVARIAN-CANCER WITH RADIOLABELED MONOCLONAL-ANTIBODIES

被引:1
|
作者
VANKRANENBURG, DL
VANKROONENBURGH, MJPG
TRIMBOS, JB
FLEUREN, GJ
PAUWELS, EKJ
机构
[1] UNIV HOSP LEIDEN,DEPT DIAGNOST RADIOL,DIV NUCL MED,BLDG 1,C4-Q,POB 9600,2300 RC LEIDEN,NETHERLANDS
[2] STATE UNIV LEIDEN HOSP,DEPT PATHOL,2333 AA LEIDEN,NETHERLANDS
[3] STATE UNIV LEIDEN HOSP,DEPT GYNECOL,2333 AA LEIDEN,NETHERLANDS
关键词
Monoclonal antibodies; Ovarian cancer; Radioimmunoscintigraphy;
D O I
10.1007/BF02390857
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
This article presents the state of the art of immunoscintigraphy (IS) of ovarian cancer. We will review the monoclonal antibodies (MoAbs) used in clinical trials: (HMFG1/2, OC125, H317, H17E2, NDOG2 and 791T/36). We conclude that none of the afore mentioned MoAbs are clearly superior and that IS cannot yet replace laparotomy for the diagnosis of overian cancer but may have a role in the follow-up of ovarian cancer, in timing second-look surgery and assessing the response/TD treatment. © 1990 Springer-Verlag.
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页码:107 / 116
页数:10
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