Measles Antibody Variation Among Different gamma-Globulin Preparations

被引:0
|
作者
Bratberg, Jeffrey P. [1 ]
Pinsky, Norman A. [2 ]
Nysse, Lana J. [2 ]
Sohni, Youvraj [3 ]
Vierkant, Robert A. [4 ]
Poland, Gregory A. [2 ,5 ]
机构
[1] Univ Rhode Isl, Dept Pharm Practice, Med, Kingston, RI 02881 USA
[2] Mayo Clin, Coll Med, Mayo Vaccine Res Grp, Rochester, MN USA
[3] Mayo Clin, Coll Med, Translat Genom Ctr, Rochester, MN USA
[4] Mayo Clin, Coll Med, Dept Biostat, Rochester, MN USA
[5] Mayo Clin, Coll Med, Program Translat Immunovirol & Biodef, Rochester, MN USA
关键词
D O I
10.1097/01.idc.0000223178.86559.09
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Among the recommended strategies for preventing measles and its complications in exposed, unvaccinated persons is passive protection by antimeasles containing immune globulin. Human intravenous and intramuscular gamma-globulins from different manufacturers were studied for manufacturer-specific variation in measles antibody titers. All gamma-globulin samples tested were seropositive for measles antibody. Titer variations were found to be clinically insignificant and thus can be used interchangeably for passive antibody protection against measles.
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页码:281 / 282
页数:2
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