NETROPSIN INHIBITS THE INCREASE OF INTRACELLULAR CA2+-DEPENDENT SERINE PROTEINASE ACTIVITY IN SPORULATING BACILLUS-MEGATERIUM

被引:2
|
作者
KUCEROVA, H
CHALOUPKA, J
机构
[1] Department of Cell and Molecular Microbiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague 4
关键词
D O I
10.1007/BF02814541
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Netropsin suppressed the increase of intracellular proteolytic activity when added to B. megaterium incubated in a sporulation medium. The inhibited enzyme was a Ca2+-dependent serine proteinase. Sporulation and protein turnover in later sporulation phases were inhibited as well. Different concentrations of netropsin affected various aspects of protein catabolism differently.
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页码:10 / 14
页数:5
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