EFFECT OF TESTOSTERONE ON ADRENAL CORTICOSTEROIDOGENESIS IN LITHIUM TREATED MALE-RATS

被引：0
|
作者：
GHOSH, D [1 ]
BISWAS, NM [1 ]
CHAUDHURI, A [1 ]
GHOSH, PK [1 ]
机构：
[1] UNIV COLL SCI & TECHNOL CALCUTTA,DEPT PHYSIOL,REPROD PHYSIOL UNIT,CALCUTTA,INDIA
来源：
ACTA PHYSIOLOGICA HUNGARICA | 1990年 / 75卷 / 04期
关键词：
TESTOSTERONE; ADRENAL CORTICOSTEROIDOGENESIS; LITHIUM; CORTICOSTERONE;
D O I：
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中图分类号：
学科分类号：
摘要：
Lithium chloride at a dose of 200 mug/100 g body weight/day given for 21 days caused a significant increase in adrenal weight, adrenal 5-ene-3-beta-hydroxysteroid dehydrogenase (5-ene-3-beta-HSD) activity along with elevation in serum level of corticosterone on the 22nd day in the rat. Administration of testosterone for the last 14 days to lithium treated rats caused a significant decrease in adrenal weight, adrenal 5-ene-3-beta-HSD activity and serum level of corticosterone in comparison to lithium treated animals.
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页码：267 / 270
页数：4
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