CYTOKINES AND IMMUNE SERA MODULATE CYTOADHERENCE OF PLASMODIUM-FALCIPARUM INFECTED ERYTHROCYTES TO HUMAN ENDOTHELIAL-CELLS

被引：0
|
作者：
RINGWALD, P [1 ]
LEBRAS, J [1 ]
SAVEL, J [1 ]
机构：
[1] UNIV PARIS 05,BIOL PARASITAIRE LAB,F-75006 PARIS,FRANCE
来源：
COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES | 1992年 / 186卷 / 03期
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中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In vitro binding capacity of erythrocytes infected with P. falciparum and the modulation of cytoadherence on human endothelial cells by cytokines and sera from semi immune subjects in relation to cytoadherence were studied. Tumor necrosis factor and interleukin-3, alone or in combination with granulocyte macrophage-colony stimulating factor, enhanced in vitro cytoadherence. Contrary to pooled immune sera, patients' sera obtained during acute or convalescent phase did not reverse nor inhibit in vitro cytoadherence.
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页码：215 / 225
页数：11
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