The effects of sulfur dioxide inhalation and antioxidant vitamins on red blood cell lipoperoxidation

被引:34
|
作者
Etlik, O [1 ]
Tomur, A [1 ]
Kutman, MN [1 ]
Yorukan, S [1 ]
Duman, O [1 ]
机构
[1] HACETTEPE UNIV,FAC MED,DEPT PHYSIOL,TR-06100 ANKARA,TURKEY
关键词
D O I
10.1006/enrs.1995.1063
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
An attempt was made to determine whether sulfur dioxide (SO2) inhalation at 10 ppm, 1 hr daily, for 30 days induces oxidant stress and whether vitamin E (40 mg/kg) together with vitamin C (200 mg/kg), administered intraperitoneally once in every 3 days, can reduce the damage in red blood cell membranes of guinea pigs. Malonyldialdehyde (MDA) levels, osmotic fragility ratios, and methemoglobin and sulfhemoglobin values were significantly higher in the SO2-treated group compared with the control group (P < 0.05), and marked decreases in MDA levels and osmotic fragility ratios were determined in the group treated with SO2 + antioxidant vitamins (P < 0.05). (C) 1995 Academic Press, Inc.
引用
收藏
页码:25 / 28
页数:4
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