ROLE OF MOTILIN IN THE CONTROL OF INTESTINAL-ABSORPTION, AND GASTRIC AND BILIARY SECRETIONS IN THE RAT

被引：6
|
作者：
NASSAR, CF
ABDALLAH, LE
ATALLAH, JB
机构：
[1] Department of Physiology, American University of Beirut, Beirut
来源：
REGULATORY PEPTIDES | 1994年 / 50卷 / 03期
关键词：
MOTILIN; PROLINE ABSORPTION; GASTRIC SECRETION; CHOLERESIS;
D O I：
10.1016/0167-0115(94)90009-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The effects of motilin on proline absorption and gastric and biliary secretions were examined in the rat. Prolonged intravenous administration of motilin (50 pmol/kg/min) significantly inhibited (P<0.05) proline transport across the jejunum and reduced basal acid secretion to 40 % of control value. The same concentration of motilin induced choleresis and increased bile output by 32%. Incubation of intestinal strips with different concentrations of motilin produced a dose-dependent inhibitory pattern of proline accumulation in the intestinal cells.
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页码：291 / 295
页数：5
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